[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"item-191":3,"related-191":68},{"id":4,"title":5,"url":6,"summary":7,"summary_zh":8,"content":9,"source_name":10,"source_url":8,"published_at":11,"category":12,"cover_url":8,"hotness":13,"is_selected":14,"score":15,"score_detail":16,"sources":23,"tags":25,"primary_topic":31,"secondary_topics":37,"classification":38,"search_phrases":62,"slug":65,"view_count":66,"doi":8,"paper":8,"created_at":67},191,"棉蚜适应新寄主的开关找到了——中国农科院棉花所揭示DNA甲基化重编程机制","https:\u002F\u002Fnew.qq.com\u002Frain\u002Fa\u002F20260803A032SA00","中国农业科学院棉花研究所棉花虫害防控与生物安全创新团队研究发现,棉蚜通过DNA甲基化重编程,实现从解毒生存到建立种群的时序性适应策略,研究成果发表于Journal of Advanced Research。研究构建了棉蚜寄主转换的动态表观遗传图谱,发现棉蚜在适应新寄主过程中全基因组DNA甲基化水平呈先升后降趋势,核心调控因子在早期优先激活棉蚜解毒基因帮助克服新寄主的化学防御,随后激活繁殖基因保障种群建立,为开发棉蚜新型绿色防控技术与可持续害虫管理提供了理论支撑。",null,"window.DATA = {\"url\":\"https:\u002F\u002Fview.inews.qq.com\u002Fa\u002F20260803A032SA00\",\"article_id\":\"20260803A032SA00\",\"atype\":\"0\",\"article_type\":\"0\",\"title\":\"棉蚜适应新寄主的“开关”找到了\",\"desc\":\"近日，中国农业科学院棉花研究所棉花虫害防控与生物安全创新团队研究发现棉蚜通过DNA甲基化重编程，实现从解毒生存到建立种群的时序性适应策略。相关研究成果发表在《前沿研究杂志（Journal of Advanced Research）》上。棉蚜是世界性重大害虫，寄主范围广泛，并在长期进化中形成了寄主专化型现象，不同专化型对其寄主表现...\",\"iNewsRecommendLevel\":1,\"abstract\":\"近日，中国农业科学院棉花研究所棉花虫害防控与生物安全创新团队研究发现棉蚜通过DNA甲基化重编程，实现从解毒生存到建立种群的时序性适应策略。相关研究成果发表在《前沿研究杂志（Journal of Advanced Research）》上。棉蚜是世界性重大害虫，寄主范围广泛，并在长期进化中形成了寄主专化型现象，不同专化型对其寄主表现...\",\"catalog1\":\"agriculture\",\"ad_channel_sign\":\"news\",\"introduction\":\"\",\"media\":\"中国农业科学院\",\"media_id\":\"20124819\",\"pubtime\":\"2026-08-03 09:29:54\",\"comment_id\":\"1260803604805338\",\"political\":0,\"cmsId\":\"20260803A032SA00\",\"cms_id\":\"20260803A032SA00\",\"closeAllAd\":0,\"closeAllFavorite\":false,\"originContent\":{\"directory\":{\"enable\":2},\"text\":\"\\u003cdiv 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normal\\\"\\u003e\\u003cspan data-nest-level=\\\"10\\\" leaf=\\\"\\\"\\u003e\\u003cbr\u002F\\u003e\\u003c\u002Fspan\\u003e\\u003c\u002Fp\\u003e\\u003c\u002Fsection\\u003e\\u003c\u002Fsection\\u003e\\u003c\u002Fsection\\u003e\\u003c\u002Fsection\\u003e\\u003csection data-nest-level=\\\"5\\\"\\u003e\\u003cp data-nest-level=\\\"6\\\"\\u003e\\u003cspan data-pm-slice=\\\"0 0 []\\\"\\u003e\\u003cspan data-pm-slice=\\\"0 0 []\\\"\\u003e\\u003cspan data-pm-slice=\\\"0 0 []\\\"\\u003e\\u003cspan leaf=\\\"\\\" style=\\\"color: rgba(0, 0, 0, 0.9); font-size: 17px; font-style: normal; font-weight: normal; letter-spacing: 0.034em; line-height: 1.6\\\"\\u003e近日，中国农业科学院\\u003c\u002Fspan\\u003e\\u003c\u002Fspan\\u003e\\u003cspan leaf=\\\"\\\" style=\\\"color: rgba(0, 0, 0, 0.9); font-size: 17px; font-style: normal; font-weight: normal; letter-spacing: 0.034em; line-height: 1.6\\\"\\u003e棉花研究所\\u003c\u002Fspan\\u003e\\u003cspan leaf=\\\"\\\" style=\\\"color: rgba(0, 0, 0, 0.9); font-size: 17px; font-style: normal; font-weight: normal; letter-spacing: 0.034em; line-height: 1.6\\\"\\u003e棉花虫害防控与生物安全创新团队研究发现棉蚜通过DNA甲基化重编程，实现从解毒生存到建立种群的时序性适应策略。相关研究成果发表在\\u003cspan style=\\\"color: rgb(4, 102, 141); font-weight: bold\\\" textstyle=\\\"\\\"\\u003e《前沿研究杂志（Journal of Advanced Research）》\\u003c\u002Fspan\\u003e上。\\u003c\u002Fspan\\u003e\\u003c\u002Fspan\\u003e\\u003c\u002Fspan\\u003e\\u003c\u002Fp\\u003e\\u003c\u002Fsection\\u003e\\u003csection data-nest-level=\\\"5\\\" style=\\\"box-sizing: border-box; display: flex; flex-flow: row; justify-content: flex-start; margin: 0px\\\"\\u003e\\u003csection data-nest-level=\\\"6\\\" style=\\\"align-self: flex-end; box-sizing: border-box; display: inline-block; flex: 0 0 0%; height: auto; margin: 0px 4px 0px 0px; vertical-align: bottom; width: auto\\\"\\u003e\\u003csection data-nest-level=\\\"7\\\" style=\\\"-moz-transform: perspective(0px); -o-transform: perspective(0px); -webkit-transform: perspective(0px); box-sizing: border-box; transform: perspective(0px); transform-style: flat\\\"\\u003e\\u003csection data-nest-level=\\\"8\\\" style=\\\"-moz-transform: rotateX(180deg); -o-transform: rotateX(180deg); -webkit-transform: rotateX(180deg); box-sizing: border-box; text-align: center; transform: rotateX(180deg)\\\"\\u003e\\u003csection data-nest-level=\\\"9\\\" style=\\\"background-color: rgb(28, 136, 136); box-sizing: border-box; display: inline-block; height: 10px; overflow: hidden; vertical-align: top; width: 3px\\\"\\u003e\\u003csvg data-nest-level=\\\"10\\\" style=\\\"float: left; line-height: 0; vertical-align: top; width: 0\\\" viewBox=\\\"0 0 1 1\\\"\\u003e\\u003c\u002Fsvg\\u003e\\u003c\u002Fsection\\u003e\\u003c\u002Fsection\\u003e\\u003c\u002Fsection\\u003e\\u003c\u002Fsection\\u003e\\u003csection data-nest-level=\\\"6\\\" style=\\\"align-self: flex-end; box-sizing: border-box; display: inline-block; flex: 0 0 0%; height: auto; vertical-align: bottom; width: auto\\\"\\u003e\\u003csection data-nest-level=\\\"7\\\" style=\\\"-moz-transform: perspective(0px); -o-transform: perspective(0px); -webkit-transform: perspective(0px); box-sizing: border-box; transform: perspective(0px); transform-style: flat\\\"\\u003e\\u003csection data-nest-level=\\\"8\\\" style=\\\"-moz-transform: rotateX(180deg); -o-transform: rotateX(180deg); -webkit-transform: rotateX(180deg); box-sizing: border-box; margin: 0px; text-align: center; transform: rotateX(180deg)\\\"\\u003e\\u003csection data-nest-level=\\\"9\\\" style=\\\"background-color: rgb(28, 136, 136); box-sizing: border-box; display: inline-block; height: 16px; overflow: hidden; vertical-align: top; width: 3px\\\"\\u003e\\u003csvg data-nest-level=\\\"10\\\" style=\\\"float: left; line-height: 0; vertical-align: top; width: 0\\\" viewBox=\\\"0 0 1 1\\\"\\u003e\\u003c\u002Fsvg\\u003e\\u003c\u002Fsection\\u003e\\u003c\u002Fsection\\u003e\\u003c\u002Fsection\\u003e\\u003c\u002Fsection\\u003e\\u003csection data-nest-level=\\\"6\\\" style=\\\"align-self: flex-end; border-bottom: 1px solid rgb(28, 136, 136); border-bottom-right-radius: 0px; box-sizing: border-box; display: inline-block; flex: 0 0 auto; height: auto; margin: 0px; padding: 4px 4px 4px 11px; vertical-align: bottom; width: 100px\\\"\\u003e\\u003csection data-nest-level=\\\"7\\\" style=\\\"box-sizing: border-box; text-align: justify\\\"\\u003e\\u003cp data-nest-level=\\\"8\\\" style=\\\"box-sizing: border-box; margin: 0px; padding: 0px; white-space: normal\\\"\\u003e\\u003cspan data-nest-level=\\\"9\\\" leaf=\\\"\\\"\\u003e\\u003cbr\u002F\\u003e\\u003c\u002Fspan\\u003e\\u003c\u002Fp\\u003e\\u003c\u002Fsection\\u003e\\u003c\u002Fsection\\u003e\\u003c\u002Fsection\\u003e\\u003c\u002Fsection\\u003e\\u003c\u002Fsection\\u003e\\u003csection nodeleaf=\\\"\\\" style=\\\"margin-bottom: 8px; margin-top: 8px; text-align: center\\\"\\u003e\\u003c!--IMG_0--\\u003e\\u003c\u002Fsection\\u003e\\u003cp data-pm-slice=\\\"0 0 []\\\" style=\\\"margin-bottom: 8px\\\"\\u003e\\u003cspan leaf=\\\"\\\" style=\\\"color: rgba(0, 0, 0, 0.9); font-size: 17px; font-style: normal; font-weight: normal; letter-spacing: 0.034em; line-height: 1.6\\\"\\u003e棉蚜是世界性重大害虫，寄主范围广泛，并在长期进化中形成了寄主专化型现象，不同专化型对其寄主表现出高度适应性。棉蚜如何跨越屏障完成新寄主适应的分子机制尚不清楚。\\u003c\u002Fspan\\u003e\\u003c!--NO_AD_0--\\u003e\\u003c!--EOP_0--\\u003e\\u003c\u002Fp\\u003e\\u003c!--PARAGRAPH_0--\\u003e\\u003cp style=\\\"margin-bottom: 8px\\\"\\u003e\\u003cspan leaf=\\\"\\\" style=\\\"color: rgba(0, 0, 0, 0.9); font-size: 17px; font-style: normal; font-weight: normal; letter-spacing: 0.034em; line-height: 1.6\\\"\\u003e该研究构建了棉蚜寄主转换的动态表观遗传图谱，发现棉蚜在适应新寄主过程中，全基因组DNA甲基化水平呈先升后降趋势，核心调控因子发挥表观遗传开关作用。进一步研究发现，该核心调控因子在早期优先激活棉蚜解毒基因，帮助棉蚜克服新寄主的化学防御，随后激活繁殖基因保障棉蚜种群建立。该成果为开发棉蚜新型绿色防控技术与可持续害虫管理提供了理论支撑。\\u003c\u002Fspan\\u003e\\u003c!--NO_AD_1--\\u003e\\u003c!--EOP_1--\\u003e\\u003c\u002Fp\\u003e\\u003c!--PARAGRAPH_1--\\u003e\\u003cp style=\\\"margin-bottom: 8px\\\"\\u003e\\u003cspan leaf=\\\"\\\" style=\\\"color: rgba(0, 0, 0, 0.9); font-size: 17px; 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0px\\\"\\u003e\\u003cspan style=\\\"color: rgb(136, 136, 136); font-size: 15px\\\" textstyle=\\\"\\\"\\u003e丨棉花所\\u003c\u002Fspan\\u003e\\u003c\u002Fspan\\u003e\\u003cspan data-nest-level=\\\"4\\\" data-pm-slice=\\\"0 0 []\\\"\\u003e\\u003cspan data-nest-level=\\\"5\\\" leaf=\\\"\\\" style=\\\"-webkit-tap-highlight-color: transparent; -webkit-text-stroke-width: 0px; background-color: rgb(255, 255, 255); box-sizing: border-box !important; color: rgba(0, 0, 0, 0.9); flex-direction: column; font-size: 17px; font-style: normal; font-variant-caps: normal; font-variant-ligatures: normal; font-weight: normal; letter-spacing: 0.034em; line-height: 1.6; margin: 0px; max-width: none !important; orphans: 2; outline: 0px; overflow-wrap: break-word !important; padding: 0px; text-align: center; text-decoration-color: initial; text-decoration-style: initial; text-decoration-thickness: initial; text-indent: 0px; text-transform: none; visibility: visible; widows: 2; word-spacing: 0px\\\"\\u003e\\u003cbr\u002F\\u003e\\u003c\u002Fspan\\u003e\\u003c\u002Fspan\\u003e\\u003c\u002Fsection\\u003e\\u003csection class=\\\"js_darkmode__11\\\" data-nest-level=\\\"3\\\" data-pm-slice=\\\"0 0 []\\\" style=\\\"-webkit-tap-highlight-color: transparent; -webkit-text-stroke-width: 0px; background-color: rgb(255, 255, 255); box-sizing: border-box !important; color: rgba(0, 0, 0, 0.9); font-size: 17px; font-style: normal; font-variant-caps: normal; font-variant-ligatures: normal; font-weight: 400; letter-spacing: 0.544px; margin: 0px; max-width: 100%; orphans: 2; outline: 0px; overflow-wrap: break-word !important; padding: 0px; text-align: center; text-decoration-color: initial; text-decoration-style: initial; text-indent: 0px; text-transform: none; visibility: visible; white-space: normal; widows: 2; word-spacing: 0px\\\"\\u003e\\u003cspan leaf=\\\"\\\" style=\\\"-webkit-tap-highlight-color: transparent; -webkit-text-stroke-width: 0px; background-color: rgb(255, 255, 255); box-sizing: border-box !important; color: rgba(0, 0, 0, 0.9); flex-direction: column; font-size: 17px; font-style: normal; font-variant-caps: normal; font-variant-ligatures: normal; font-weight: normal; letter-spacing: 0.034em; line-height: 1.6; margin: 0px; max-width: none !important; orphans: 2; outline: 0px; overflow-wrap: break-word !important; padding: 0px; text-align: center; text-decoration-color: initial; text-decoration-style: initial; text-decoration-thickness: initial; text-indent: 0px; text-transform: none; visibility: visible; widows: 2; word-spacing: 0px\\\"\\u003e\\u003cspan style=\\\"color: rgb(136, 136, 136); font-size: 15px\\\" textstyle=\\\"\\\"\\u003e作者丨\\u003c\u002Fspan\\u003e\\u003c\u002Fspan\\u003e\\u003cspan data-pm-slice=\\\"0 0 []\\\"\\u003e\\u003cspan leaf=\\\"\\\" style=\\\"-webkit-tap-highlight-color: transparent; -webkit-text-stroke-width: 0px; background-color: rgb(255, 255, 255); box-sizing: border-box !important; color: rgba(0, 0, 0, 0.9); flex-direction: column; font-size: 17px; font-style: normal; font-variant-caps: normal; font-variant-ligatures: normal; font-weight: normal; letter-spacing: 0.034em; line-height: 1.6; margin: 0px; max-width: none !important; orphans: 2; outline: 0px; overflow-wrap: break-word !important; padding: 0px; text-align: center; text-decoration-color: initial; text-decoration-style: initial; text-decoration-thickness: initial; text-indent: 0px; text-transform: none; visibility: visible; widows: 2; word-spacing: 0px\\\"\\u003e\\u003cspan style=\\\"color: rgb(136, 136, 136); font-size: 15px\\\" textstyle=\\\"\\\"\\u003e高雪珂\\u003c\u002Fspan\\u003e\\u003c\u002Fspan\\u003e\\u003c\u002Fspan\\u003e\\u003c\u002Fsection\\u003e\\u003csection class=\\\"js_darkmode__11\\\" data-nest-level=\\\"3\\\" data-pm-slice=\\\"0 0 []\\\" style=\\\"-webkit-tap-highlight-color: transparent; -webkit-text-stroke-width: 0px; background-color: rgb(255, 255, 255); box-sizing: border-box !important; color: rgba(0, 0, 0, 0.9); font-size: 17px; font-style: normal; font-variant-caps: normal; font-variant-ligatures: normal; font-weight: 400; letter-spacing: 0.544px; margin: 0px; max-width: 100%; orphans: 2; outline: 0px; overflow-wrap: break-word !important; padding: 0px; text-align: center; text-decoration-color: initial; text-decoration-style: initial; text-indent: 0px; text-transform: none; visibility: visible; white-space: normal; widows: 2; word-spacing: 0px\\\"\\u003e\\u003cspan leaf=\\\"\\\" style=\\\"-webkit-tap-highlight-color: transparent; -webkit-text-stroke-width: 0px; background-color: rgb(255, 255, 255); box-sizing: border-box !important; color: rgba(0, 0, 0, 0.9); flex-direction: column; font-size: 17px; font-style: normal; font-variant-caps: normal; font-variant-ligatures: normal; font-weight: normal; letter-spacing: 0.034em; line-height: 1.6; margin: 0px; max-width: none !important; orphans: 2; outline: 0px; overflow-wrap: break-word !important; padding: 0px; text-align: center; text-decoration-color: initial; text-decoration-style: initial; text-decoration-thickness: initial; text-indent: 0px; text-transform: none; visibility: visible; widows: 2; word-spacing: 0px\\\"\\u003e\\u003cspan style=\\\"color: rgb(136, 136, 136); font-size: 15px\\\" textstyle=\\\"\\\"\\u003e通讯员丨梁冰\\u003c\u002Fspan\\u003e\\u003c\u002Fspan\\u003e\\u003cspan data-pm-slice=\\\"1 1 [\\u0026#34;para\\u0026#34;,{\\u0026#34;tagName\\u0026#34;:\\u0026#34;section\\u0026#34;,\\u0026#34;attributes\\u0026#34;:{\\u0026#34;style\\u0026#34;:\\u0026#34;box-sizing: border-box;font-style: normal;font-weight: 400;text-align: justify;font-size: 16px;colo\n[…全文已截断…]","中国农业科学院棉花研究所 2026-08-03","2026-08-03T00:00:00Z","报道",10,false,85,{"impact":17,"substance":17,"depth":18,"authority":19,"freshness":20,"relevant":21,"comment":22},22,18,14,9,1,"国家级科研机构发布棉蚜寄主适应机制新发现，具科研价值，但属细分领域进展，影响范围有限。",[24],{"name":10,"url":6},[26,27,28,29,30],"中国农科院","绿色防控","棉花所","棉蚜","DNA甲基化",{"code":32,"slug":33,"name":34,"path":35,"parent_code":36},"A6","cash-crops","棉麻糖与特色经作","\u002Ftopic\u002Ffield-crops\u002Fcash-crops","A",[],{"status":39,"locked":14,"version":40,"method":41,"evidence":42},"classified","2026-10-22.2","rules",{"candidates":43,"agricultural_evidence":46},[44,51,57],{"code":32,"score":45,"supported":46,"title":47,"abstract":49,"tags":50},11,true,[48],"棉花",[48],[],{"code":52,"score":53,"supported":46,"title":54,"abstract":55,"tags":56},"F4",4,[],[27],[27],{"code":58,"score":21,"supported":14,"title":59,"abstract":60,"tags":61},"H8",[],[],[27],[63,64],"中国农科院 绿色防控 DNA甲基化 棉花所","中国农科院 绿色防控","中国农科院绿色防控DNA甲基化棉花所-191",7,"2026-08-04T01:15:44.465753Z",{"total":69,"page":21,"page_size":69,"items":70},6,[71,106,158,201,237,279],{"id":72,"title":73,"url":74,"summary":75,"summary_zh":8,"content":76,"source_name":77,"source_url":8,"published_at":11,"category":12,"cover_url":8,"hotness":13,"is_selected":14,"score":78,"score_detail":79,"sources":81,"tags":83,"primary_topic":87,"secondary_topics":88,"classification":89,"search_phrases":101,"slug":104,"view_count":69,"doi":8,"paper":8,"created_at":105},280,"中国农业科学院棉花所破解棉蚜适应新寄主「开关」——首次构建寄主转换动态表观遗传图谱,DNA甲基化重编程机制","https:\u002F\u002Fcri.caas.cn\u002Fxwdt\u002Fmtbd\u002Fbe461616691b43d9952cad65d618846d.htm","近日,中国农业科学院棉花研究所棉花虫害防控与生物安全创新团队研究发现棉蚜通过DNA甲基化重编程,实现从解毒生存到建立种群的时序性适应策略,相关研究成果发表在《前沿研究杂志(Journal of Advanced Research)》上。棉蚜是世界性重大害虫,寄主范围广泛,并在长期进化中形成了寄主专化型现象,不同专化型对其寄主表现出高度适应性;棉蚜如何跨越屏障完成新寄主适应的分子机制尚不清楚。研究团队构建了棉蚜寄主转换的动态表观遗传图谱,发现棉蚜在适应新寄主过程中,全基因组DNA甲基化水平呈先升后降趋势,核心调控因子发挥表观遗传开关作用。进一步研究发现,该核心调控因子在早期优先激活棉蚜解毒基因,帮助棉蚜克服新寄主的化学防御,随后激活繁殖基因保障棉蚜种群建立。该成果为开发棉蚜新型绿色防控技术与可持续害虫管理提供了理论支撑,得到河南省自然科学基金、国家重点研发计划等项目支持。","近日，中国农业科学院棉花研究所棉花虫害防控与生物安全创新团队研究发现棉蚜通过DNA甲基化重编程，实现从解毒生存到建立种群的时序性适应策略。相关研究成果发表在《前沿研究杂志（Journal of Advanced Research）》上。\n\n棉蚜是世界性重大害虫，寄主范围广泛，并在长期进化中形成了寄主专化型现象，不同专化型对其寄主表现出高度适应性。棉蚜如何跨越屏障完成新寄主适应的分子机制尚不清楚。\n\n该研究构建了棉蚜寄主转换的动态表观遗传图谱，发现棉蚜在适应新寄主过程中，全基因组DNA甲基化水平呈先升后降趋势，核心调控因子发挥表观遗传开关作用。进一步研究发现，该核心调控因子在早期优先激活棉蚜解毒基因，帮助棉蚜克服新寄主的化学防御，随后激活繁殖基因保障棉蚜种群建立。该成果为开发棉蚜新型绿色防控技术与可持续害虫管理提供了理论支撑。\n\n该研究得到河南省自然科学基金、国家重点研发计划等项目支持。","中国农科院网 2026-08-03",82,{"impact":17,"substance":17,"depth":18,"authority":19,"freshness":69,"relevant":21,"comment":80},"国家级科研机构发布棉蚜表观遗传研究突破，对农业害虫防控有重要科学价值，但时效性稍差。",[82],{"name":77,"url":74},[26,28,29,30,84,85,86],"表观遗传","寄主适应","Journal of Advanced Research",{"code":32,"slug":33,"name":34,"path":35,"parent_code":36},[],{"status":39,"locked":14,"version":40,"method":41,"evidence":90},{"candidates":91,"agricultural_evidence":46},[92,96],{"code":32,"score":45,"supported":46,"title":93,"abstract":94,"tags":95},[48],[48],[],{"code":52,"score":97,"supported":46,"title":98,"abstract":99,"tags":100},3,[],[27],[],[102,103],"中国农科院 寄主适应 表观遗传 DNA甲基化","中国农科院 寄主适应","中国农科院寄主适应表观遗传DNA甲基化-280","2026-08-07T23:57:49.864553Z",{"id":107,"title":108,"url":109,"summary":110,"summary_zh":8,"content":111,"source_name":112,"source_url":8,"published_at":113,"category":12,"cover_url":8,"hotness":13,"is_selected":46,"score":114,"score_detail":115,"sources":120,"tags":122,"primary_topic":127,"secondary_topics":128,"classification":129,"search_phrases":152,"slug":155,"view_count":156,"doi":8,"paper":8,"created_at":157},944,"棉花专属知识大语言模型「棉芯1.0」发布 中国棉花产业迈入AI+科研+生产融合新阶段","https:\u002F\u002Fnews.gmw.cn\u002F2026-08\u002F26\u002Fcontent_38963850.htm","8月24日中国农业科学院棉花研究所联合西部农业研究中心发布全球首个棉花领域专属知识大语言模型「棉芯1.0」(CottonMind1.0)，采用「网页端+小程序端」双端设计：网页端为科研人员提供云端智研工作台(AI检索、文献加速阅读、知识图谱)，小程序端成为棉农随身「农技专家」(AI问答、拍照诊断、专家咨询)。模型已整合41680篇中外文科研文献、2000余项专利与国家标准、559部专业著作、1806条审定品种信息，覆盖基因功能、性状调控、品种选育、栽培管理、病虫害防控等全维度专业知识，并支持中英多语言服务。项目组负责人杨作仁表示，棉芯1.0打通了科研成果转化「最后一公里」，可服务于政府部门种植规划、防控策略与产业政策制定。","![Image 1](https:\u002F\u002Fimg.gmw.cn\u002Fpic\u002FgmwLogo_share.jpg)\n\n点击右上角![Image 2](https:\u002F\u002Fimg.gmw.cn\u002Fpic\u002Fmgmw\u002Ficonshare.png)微信好友\n\n![Image 3](https:\u002F\u002Fimg.gmw.cn\u002Fpic\u002Fmgmw\u002Fpengyouquan.png)朋友圈\n\n![Image 4](https:\u002F\u002Fimg.gmw.cn\u002Fpic\u002Fmgmw\u002Flayershare.png)\n\n点击浏览器下方“![Image 5](https:\u002F\u002Fimg.gmw.cn\u002Fpic\u002Fmgmw\u002Flineshare.png)”分享微信好友Safari浏览器请点击“![Image 6](https:\u002F\u002Fimg.gmw.cn\u002Fpic\u002Fmgmw\u002Fshare.png)”按钮\n\n![Image 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棉花专属知识大语言模型“棉芯1.0”发布\n\n来源：[光明网-《光明日报》](https:\u002F\u002Fepaper.gmw.cn\u002Fgmrb\u002Fhtml\u002Fcontent\u002F202608\u002F26\u002Fcontent_23394.html)2026-08-26 05:50\n\n[](https:\u002F\u002Fnews.gmw.cn\u002F2026-08\u002F26\u002Fcontent_38963850.htm)[X](javascript:;)[](https:\u002F\u002Fnews.gmw.cn\u002F2026-08\u002F26\u002Fcontent_38963850.htm)\n\n调查问题加载中，请稍候。\n\n若长时间无响应，请刷新本页面\n\n**光明日报京8月25日电 记者杨舒**从中国农业科学院棉花研究所获悉，24日，该所联合中国农业科学院西部农业研究中心正式发布全球首个棉花领域专属知识大语言模型——“棉芯1.0”（CottonMind1.0），标志着我国棉花产业迈入“AI+科研+生产”深度融合的新阶段。\n\n“棉芯1.0”以“网页端+小程序端”双端设计，分别瞄准科研创新与田间生产两大核心场景。网页端为科研人员提供云端智研工作台，集成AI智能检索、文献加速阅读、知识图谱可视化等功能。小程序端可以成为棉农的随身“农技专家”，提供AI问答、拍照诊断、专家在线咨询等服务，打破了传统农技服务的时空壁垒。此外，“棉芯1.0”全平台支持中文、英文等多语言服务，为国际棉花科研协作搭建了数字化桥梁。\n\n项目组负责人杨作仁介绍，“棉芯1.0”系统已整合全球41680篇中外文科研文献、2000余项专利与国家标准、559部专业著作、1806条审定品种信息，覆盖基因功能、性状调控、品种选育、栽培管理、病虫害防控等全维度专业知识。\n\n“棉芯1.0”的发布，是我国智慧农业建设在经济作物领域的重要突破。它打通了科研成果转化“最后一公里”，构建起“科研创新—技术推广—生产应用—数据反哺”的闭环生态。同时，“棉芯1.0”通过全产业数据归集与大数据分析，可为政府部门制定种植规划、防控策略与产业扶持政策提供科学数据支撑。\n\n《光明日报》（2026年08月26日 08版）\n\n[ 责编：赵靓 ]\n\n阅读剩余全文（）\n\n![Image 15](https:\u002F\u002Fimg.gmw.cn\u002Fcontent_banner\u002Fcontent_840x120_qrcodes.jpg)\n\n## 值班总编推荐\n\n*   [重视电动车治理是对道路交通安全负责](https:\u002F\u002Fguancha.gmw.cn\u002F2026-08\u002F25\u002Fcontent_38963649.htm)\n*   [高校选课季，如何让“金课”广受欢迎？](https:\u002F\u002Fnews.gmw.cn\u002F2026-08\u002F25\u002Fcontent_38961616.htm)\n*   [第二届世界人形机器人运动会:\"智芯\"点亮\"冰丝带\"](https:\u002F\u002Fnews.gmw.cn\u002F2026-08\u002F25\u002Fcontent_38961723.htm)\n\n## 追思\n\n[![Image 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[光明网邮箱](https:\u002F\u002Fmail.gmw.cn\u002F)\n*   [网站地图](https:\u002F\u002Fwww.gmw.cn\u002Fmap.htm)\n\n![Image 20](https:\u002F\u002Fchannel-analysis.gmw.cn\u002F1.gif?s=1787702980444&cl=4108&pd=2026-08-26&ci=38963850&r=https:\u002F\u002Fnews.gmw.cn\u002F2026-08\u002F26\u002Fcontent_38963850.htm&at=%E8%B5%B5%E9%9D%93&tt=%E6%A3%89%E8%8A%B1%E4%B8%93%E5%B1%9E%E7%9F%A5%E8%AF%86%E5%A4%A7%E8%AF%AD%E8%A8%80%E6%A8%A1%E5%9E%8B%E2%80%9C%E6%A3%89%E8%8A%AF1.0%E2%80%9D%E5%8F%91%E5%B8%83%20_%E5%85%89%E6%98%8E%E7%BD%91)\n\n[](https:\u002F\u002Fwww.facebook.com\u002Fguangmingonline)[](https:\u002F\u002Fwww.facebook.com\u002Fguangmingonline)\n\n[](https:\u002F\u002Ftwitter.com\u002FGuangming_Daily)[](https:\u002F\u002Ftwitter.com\u002FGuangming_Daily)\n\n[](javascript:;)","光明日报 2026-08-26 第8版","2026-08-26T00:00:00Z",88,{"impact":116,"substance":17,"depth":117,"authority":118,"freshness":13,"relevant":21,"comment":119},25,16,15,"全球首个棉花专属大模型发布，标志产业迈入AI融合新阶段，信息详实，权威央媒报道，时效性强。",[121],{"name":112,"url":109},[123,26,124,28,125,126],"智慧农业","大语言模型","棉芯1.0","经济作物",{"code":32,"slug":33,"name":34,"path":35,"parent_code":36},[],{"status":39,"locked":14,"version":40,"method":41,"evidence":130},{"candidates":131,"agricultural_evidence":46},[132,136,142,147],{"code":32,"score":45,"supported":46,"title":133,"abstract":134,"tags":135},[48],[48],[],{"code":137,"score":97,"supported":46,"title":138,"abstract":139,"tags":141},"G1",[],[140],"成果转化",[],{"code":143,"score":21,"supported":14,"title":144,"abstract":145,"tags":146},"I1",[],[],[123],{"code":148,"score":21,"supported":14,"title":149,"abstract":150,"tags":151},"I2",[],[],[124],[153,154],"中国农科院 大语言模型 智慧农业 经济作物","中国农科院 大语言模型","中国农科院大语言模型智慧农业经济作物-944",5,"2026-08-26T00:09:29.400381Z",{"id":159,"title":160,"url":161,"summary":162,"summary_zh":8,"content":163,"source_name":164,"source_url":8,"published_at":165,"category":12,"cover_url":8,"hotness":13,"is_selected":14,"score":166,"score_detail":167,"sources":171,"tags":173,"primary_topic":178,"secondary_topics":179,"classification":180,"search_phrases":196,"slug":199,"view_count":53,"doi":8,"paper":8,"created_at":200},306,"中国农科院烟草所研发新型双金属人工水解酶——生物膜清除率超80%、杀菌率超85%,登《德国应用化学》封面","https:\u002F\u002Fwww.toutiao.com\u002Farticle\u002F7670743194199441983\u002F","中国农业科学院烟草研究所烟草病虫害绿色防控创新团队成功研发一种新型双金属人工水解酶,将高活性Ce4+引入金属有机框架,构建具有双金属共定位活性中心的人工水解酶。该酶可高效水解糖苷键、实现对细菌生物膜多糖骨架的靶向降解,生物膜清除率超80%,杀菌率超85%。相关成果发表在国际顶级期刊《德国应用化学》(Angewandte Chemie International Edition, IF=17.6),获选为当期封面文章并被列为期刊热点论文。","## 农科院烟草所研发出新型双金属人工水解酶，开辟细菌性病害防控药剂创制新路径\n\n2026-08-06 10:41·[世界农化网](https:\u002F\u002Fwww.toutiao.com\u002Fc\u002Fuser\u002Ftoken\u002FMS4wLjABAAAA-zO4FIkTaHs7RWfbEvMWSg5481TH8enpiYeOz5Z1r0U\u002F?source=tuwen_detail)\n\n**世界农化网中文网**报道：近日，中国农业科学院烟草研究所烟草病虫害绿色防控创新团队成功研发一种新型双金属人工水解酶，可高效降解细菌生物膜并杀死细菌，为细菌性病害绿色防控药剂的创制提供了全新设计策略。相关成果发表在国际顶级期刊《德国应用化学（Angewandte Chemie International Edition）》（IF=17.6），获选为当期封面文章，并被列为期刊热点论文（Hot Paper）。\n\n细菌生物膜是病原菌通过群体感应形成的胞外屏障，其结构完整性高度依赖于胞外多糖等大分子交织形成的骨架网络，可显著削弱防治药剂渗透与宿主免疫识别，是导致防治药剂防效骤降、田间病害反复暴发的核心诱因。\n\n针对制约农业细菌性病害防治的技术瓶颈，研究团队将高活性Ce4+引入金属有机框架，构建出具有双金属共定位活性中心的人工水解酶；通过密度泛函理论计算，首次阐明其区别于天然水解酶的独特催化路径。该酶具有良好的生物安全性和环境耐受性，可高效水解糖苷键，实现对细菌生物膜多糖骨架的靶向降解，生物膜清除率超80%，杀菌率超85%。\n\n![Image 1](https:\u002F\u002Fp3-sign.toutiaoimg.com\u002Ftos-cn-i-axegupay5k\u002Fcdccf90ebfd04a03bd2f35d88ecf8986~tplv-tt-origin-web:gif.jpeg?_iz=58558&from=article.pc_detail&lk3s=953192f4&x-expires=1786838058&x-signature=dKuFjAy4MNfETDD4afKqmWKTcqQ%3D)\n该成果突破传统杀菌剂依赖，首次将人工水解酶应用于生物膜的靶向清除，基于″解膜-杀菌″联动机制开辟了绿色防控新路径，对破解当前细菌性病害防治无特效药可用的产业困境具有重要现实意义。","中国农业科学院烟草所\u002F世界农化网 2026-08-06","2026-08-06T00:00:00Z",86,{"impact":116,"substance":17,"depth":18,"authority":168,"freshness":169,"relevant":21,"comment":170},13,8,"国家级科研机构重大突破，登顶刊封面，数据详实，对农业细菌病害防控有重要价值。",[172],{"name":164,"url":161},[26,27,174,175,176,177],"烟草所","人工水解酶","细菌生物膜","Angewandte Chemie",{"code":32,"slug":33,"name":34,"path":35,"parent_code":36},[],{"status":39,"locked":14,"version":40,"method":41,"evidence":181},{"candidates":182,"agricultural_evidence":46},[183,188,192],{"code":32,"score":45,"supported":46,"title":184,"abstract":186,"tags":187},[185],"烟草",[185],[],{"code":52,"score":53,"supported":46,"title":189,"abstract":190,"tags":191},[],[27],[27],{"code":58,"score":21,"supported":14,"title":193,"abstract":194,"tags":195},[],[],[27],[197,198],"中国农科院 人工水解酶 细菌生物膜 绿色防控","中国农科院 人工水解酶","中国农科院人工水解酶细菌生物膜绿色防控-306","2026-08-08T23:53:55.518986Z",{"id":202,"title":203,"url":204,"summary":205,"summary_zh":8,"content":206,"source_name":207,"source_url":8,"published_at":208,"category":12,"cover_url":8,"hotness":13,"is_selected":14,"score":209,"score_detail":210,"sources":212,"tags":214,"primary_topic":217,"secondary_topics":218,"classification":219,"search_phrases":231,"slug":234,"view_count":235,"doi":8,"paper":8,"created_at":236},4766,"棉花关键技术集成助力高温逆境下产量品质效益三丰收","https:\u002F\u002Fwap.sciencenet.cn\u002Fmobile.php?cat=T&id=572667","中国农业科学院西部农业研究中心在昌吉州老龙河综合试验基地举办棉花优质高产关键技术集成示范观摩会。千亩示范方实测籽棉平均亩产601.4公斤,集成中棉113优系、中新棉1号、3号等优质多抗新品种,以及高光效群体调控、智慧棉田管理、绿色病虫害防控等成套技术,节药15%以上、人工成本降低30%以上。","科学网—\n\n## [![Image 1: 科学网](https:\u002F\u002Fwap.sciencenet.cn\u002Fstatic\u002Fimage\u002Fcommon\u002Flogo.png)](https:\u002F\u002Fwap.sciencenet.cn\u002F \"科学网\")\n\n*   [要闻](https:\u002F\u002Fwap.sciencenet.cn\u002Fmobile.php?type=news&cat=yaowen&mobile=1)\n*   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[针对无人机电子垃圾危机，天大团队《科学》发文](https:\u002F\u002Fwap.sciencenet.cn\u002Fmobile.php?type=detail&cat=T&id=572765&mobile=1)\n*   [“核聚山城?智驭靶向”：第十八届全国放射性药物与标记化合物学术交流会在重庆举办](https:\u002F\u002Fwap.sciencenet.cn\u002Fmobile.php?type=detail&cat=T&id=572754&mobile=1)\n*   [通往“器官再生之路”](https:\u002F\u002Fwap.sciencenet.cn\u002Fmobile.php?type=detail&cat=T&id=572753&mobile=1)\n*   [AI写的字，开始自带“暗号”](https:\u002F\u002Fwap.sciencenet.cn\u002Fmobile.php?type=detail&cat=T&id=572752&mobile=1)","中国科学报 科学网 2026-10-10","2026-10-10T00:00:00Z",73,{"impact":17,"substance":18,"depth":19,"authority":168,"freshness":69,"relevant":21,"comment":211},"报道中国农科院棉花高温逆境关键技术集成取得产量品质效益三丰收，属细分领域实质进展，但时效稍旧、信息增量有限，可入精选备选。",[213],{"name":207,"url":204},[123,26,48,215,216],"技术集成","高温逆境",{"code":32,"slug":33,"name":34,"path":35,"parent_code":36},[],{"status":39,"locked":14,"version":40,"method":41,"evidence":220},{"candidates":221,"agricultural_evidence":46},[222,227],{"code":32,"score":223,"supported":46,"title":224,"abstract":225,"tags":226},12,[48],[48],[48],{"code":143,"score":21,"supported":14,"title":228,"abstract":229,"tags":230},[],[],[123],[232,233],"中国农科院 棉花 高温逆境","棉花 关键技术集成 产量品质","中国农科院棉花高温逆境-4766",0,"2026-10-13T00:08:35.350655Z",{"id":238,"title":239,"url":240,"summary":241,"summary_zh":8,"content":8,"source_name":242,"source_url":8,"published_at":243,"category":12,"cover_url":8,"hotness":13,"is_selected":14,"score":166,"score_detail":244,"sources":246,"tags":248,"primary_topic":252,"secondary_topics":253,"classification":259,"search_phrases":274,"slug":277,"view_count":97,"doi":8,"paper":8,"created_at":278},2842,"中国农科院烟草所双金属人工水解酶开辟细菌性病害绿色防控新路径登Angewandte Chemie","https:\u002F\u002Fnews.qq.com\u002Frain\u002Fa\u002F20260917A03VJ100","近日,中国农业科学院烟草研究所烟草病虫害绿色防控创新团队成功研发一种新型双金属人工水解酶,可高效降解细菌生物膜并杀灭病原菌。团队将高活性铈引入金属有机框架,构建双金属人工水解酶,阐明其区别于天然酶的独特催化路径。该酶具有良好的生物安全性与环境稳定性,可精准切断细菌生物膜多糖骨架的化学键,瓦解细菌防护膜,清除率超80%,杀菌率超85%。该成果首次将人工水解酶应用于细菌生物膜靶向清除,为农作物绿色防控开辟新路径。","腾讯新闻 \u002F 中国农业科学院烟草研究所","2026-09-17T00:00:00Z",{"impact":17,"substance":17,"depth":18,"authority":19,"freshness":13,"relevant":21,"comment":245},"国家级科研机构在核心期刊发表的双金属人工水解酶成果，首次实现细菌生物膜靶向清除，数据扎实、时效性强，具备进入每日精选的价值。",[247],{"name":242,"url":240},[27,249,250,185,251],"农业科技","人工酶","生物膜",{"code":32,"slug":33,"name":34,"path":35,"parent_code":36},[254],{"code":52,"slug":255,"name":256,"path":257,"parent_code":258},"crop-protection","农药与绿色防控","\u002Ftopic\u002Finputs-equipment\u002Fcrop-protection","F",{"status":39,"locked":14,"version":40,"method":41,"evidence":260},{"candidates":261,"agricultural_evidence":46},[262,266,270],{"code":32,"score":223,"supported":46,"title":263,"abstract":264,"tags":265},[185],[185],[185],{"code":52,"score":223,"supported":46,"title":267,"abstract":268,"tags":269},[27],[27],[27],{"code":58,"score":21,"supported":14,"title":271,"abstract":272,"tags":273},[],[],[27],[275,276],"农业科技 绿色防控 人工酶 生物膜","农业科技 绿色防控","农业科技绿色防控人工酶生物膜-2842","2026-09-18T00:03:28.675103Z",{"id":280,"title":281,"url":282,"summary":283,"summary_zh":8,"content":284,"source_name":285,"source_url":8,"published_at":286,"category":12,"cover_url":8,"hotness":13,"is_selected":14,"score":287,"score_detail":288,"sources":291,"tags":293,"primary_topic":296,"secondary_topics":297,"classification":299,"search_phrases":314,"slug":317,"view_count":53,"doi":8,"paper":8,"created_at":318},1556,"中国农业科学院烟草所：双金属人工酶开辟细菌性病害绿色防控新路径（Angewandte Chemie）","https:\u002F\u002Fwww.caas.cn\u002Fxwzx\u002Fkyhd\u002F59452b198605475b991f2f29d9ea6f61.htm","近日，中国农业科学院烟草研究所烟草病虫害绿色防控创新团队成功研发一种新型双金属人工水解酶，可高效降解细菌生物膜并杀灭病原菌。该酶将高活性铈引入金属有机框架，具有良好的生物安全性与环境稳定性，清除率超 80%、杀菌率超 85%。该成果突破传统杀菌剂依赖，首次将人工水解酶应用于细菌生物膜靶向清除，打破了细菌性病害缺乏特效药的产业困境，为农作物绿色防控开辟新路径。相关成果发表在《德国应用化学》（Angewandte Chemie International Edition）上。","[English](https:\u002F\u002Fwww.caas.cn\u002Fen)[邮箱](https:\u002F\u002Fmail.caas.cn\u002F)[数字农科院](https:\u002F\u002Fi.caas.cn\u002F)[](https:\u002F\u002Fwww.caas.cn\u002Fcms\u002Fweb\u002Fsearch\u002Findex.jsp?siteID=cdb01dceb46e48488945d4465e90f221&aba=)\n\n官方微信 \n\n![Image 2](https:\u002F\u002Fwww.caas.cn\u002Fimages\u002F2023-01\u002F020ac4d3d8b6451782a8702c72604336.jpg)农科专家在线微信公众号\n\n![Image 3](https:\u002F\u002Fwww.caas.cn\u002Fimages\u002F2023-01\u002Fbf6579e4651e437db31a22cd2249b319.jpg)中国农科院微信公众号\n\n[![Image 4](https:\u002F\u002Fwww.caas.cn\u002Fstatic2022\u002Fimages\u002Fmenu_logo.png)](https:\u002F\u002Fwww.caas.cn\u002Findex.htm)\n\n*   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\n\n[返回首页](https:\u002F\u002Fwww.caas.cn\u002Findex.htm)[English](https:\u002F\u002Fwww.caas.cn\u002Fen\u002F)\n\n[首页](https:\u002F\u002Fwww.caas.cn\u002Findex.htm)-[新闻中心](https:\u002F\u002Fwww.caas.cn\u002Fxwzx\u002Findex.htm)-[科研活动](https:\u002F\u002Fwww.caas.cn\u002Fxwzx\u002Fkyhd\u002Findex.htm)\n\n分享到\n\n### 人工酶开辟细菌性病害绿色防控新路径\n\n发布时间：2026-09-01 _|_ 来源： 中国农业科学院烟草研究所 _|_ 作者：慕文静\n\n字体[小](https:\u002F\u002Fwww.caas.cn\u002Fxwzx\u002Fkyhd\u002F59452b198605475b991f2f29d9ea6f61.htm)[中](https:\u002F\u002Fwww.caas.cn\u002Fxwzx\u002Fkyhd\u002F59452b198605475b991f2f29d9ea6f61.htm)[大](https:\u002F\u002Fwww.caas.cn\u002Fxwzx\u002Fkyhd\u002F59452b198605475b991f2f29d9ea6f61.htm)\n\n近日，中国农业科学院[烟草研究所](http:\u002F\u002Ftric.caas.cn\u002F)烟草病虫害绿色防控创新团队成功研发一种新型双金属人工水解酶，可高效降解细菌生物膜并杀灭病原菌，为细菌性病害绿色防控药剂的创制提供全新设计策略。相关成果发表在《德国应用化学（Angewandte Chemie International Edition）》上。\n\n细菌生物膜是病原菌通过群体感应分泌形成的“保护壳”，其主要骨架由糖类物质交织而成，可显著削弱药剂渗透与免疫清除，导致田间防治效果大幅降低，是病害反复暴发的核心诱因。\n\n针对制约农业细菌性病害防治的技术瓶颈，研究团队将高活性铈引入金属有机框架，构建双金属人工水解酶，并阐明其区别于天然酶的独特催化路径。该酶具有良好的生物安全性与环境稳定性，可精准切断细菌生物膜多糖骨架的化学键，瓦解细菌防护膜，清除率超80%，杀菌率超85%。该成果突破传统杀菌剂依赖，首次将人工水解酶应用于细菌生物膜靶向清除，打破了细菌性病害缺乏特效药的产业困境，为农作物绿色防控开辟新路径。\n\n该研究得到国家自然科学基金和山东省自然科学基金等项目支持。（通讯员 李晓娟）\n\n论文链接：https:\u002F\u002Fdoi.org\u002F10.1002\u002Fanie.9481237\n\n![Image 8: 001.png](https:\u002F\u002Fwww.caas.cn\u002Fimages\u002F2026-09\u002Fe45c5f97ad2e4c81847a32cfe5fd39bc.png)\n\n打印本页\n\n关闭本页\n\n[院网信息发布与管理](https:\u002F\u002Fwww.caas.cn\u002Fywxxfbygl\u002Findex.htm)[最新动态](https:\u002F\u002Fwww.caas.cn\u002Fywxxfbygl\u002Findex.htm)\n\n*   [第7期“农科讲坛”举办 以农业农村现代化推动实现中国式现代化](https:\u002F\u002Fwww.caas.cn\u002Fxwzx\u002Fnkyw\u002F1c78565c9c5648c5b6f3e70d035deb07.htm)2026-08-31  \n*   [西梅浆加工色泽劣变规律被揭示](https:\u002F\u002Fwww.caas.cn\u002Fxwzx\u002Fkyhd\u002F958676b943cb4e229d3f617ba4f35e75.htm)2026-08-31  \n*   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京公网安备11010802048565号](http:\u002F\u002Fwww.beian.gov.cn\u002Fportal\u002FregisterSystemInfo?recordcode=11010802048565)","中国农业科学院·科研进展","2026-09-03T00:00:00Z",83,{"impact":289,"substance":17,"depth":18,"authority":118,"freshness":169,"relevant":21,"comment":290},20,"中国农科院烟草所开发双金属人工酶，为细菌性病害绿色防控提供新路径，发表于Angewandte Chemie，具有较高科研价值和行业影响。",[292],{"name":285,"url":282},[27,250,294,185,295],"细菌病害","生物防治",{"code":32,"slug":33,"name":34,"path":35,"parent_code":36},[298],{"code":52,"slug":255,"name":256,"path":257,"parent_code":258},{"status":39,"locked":14,"version":40,"method":41,"evidence":300},{"candidates":301,"agricultural_evidence":46},[302,306,310],{"code":52,"score":168,"supported":46,"title":303,"abstract":304,"tags":305},[27],[27],[295,27],{"code":32,"score":223,"supported":46,"title":307,"abstract":308,"tags":309},[185],[185],[185],{"code":58,"score":21,"supported":14,"title":311,"abstract":312,"tags":313},[],[],[27],[315,316],"生物防治 细菌病害 绿色防控 人工酶","生物防治 细菌病害","生物防治细菌病害绿色防控人工酶-1556","2026-09-04T00:05:31.812843Z"]