[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"item-5020":3,"related-5020":64},{"id":4,"title":5,"url":6,"summary":7,"summary_zh":8,"content":9,"source_name":10,"source_url":8,"published_at":11,"category":12,"cover_url":8,"hotness":13,"is_selected":14,"score":15,"score_detail":16,"sources":23,"tags":25,"primary_topic":31,"secondary_topics":37,"classification":38,"search_phrases":58,"slug":61,"view_count":62,"doi":8,"paper":8,"created_at":63},5020,"农业农村部召开兽药管理专题会议","https:\u002F\u002Fwww.moa.gov.cn\u002Fxw\u002Fzwdt\u002F202610\u002Ft20261015_6488628.htm","近日,农业农村部在京召开兽药管理专题会议,深入学习贯彻习近平总书记重要指示精神,落实党中央、国务院决策部署,研究交流兽药产业发展和管理情况,部署下一阶段重点工作和政策举措。农业农村部党组成员、副部长张治礼出席会议并讲话。会议指出我国兽药产业已形成较为完备的产业体系,产品供给充足、质量较高,有力支撑了养殖业健康发展、动物产品质量安全和公共卫生安全。下一步将研究优化审批程序、提高水产和宠物用兽药等注册评审效率,持续推进兽用抗菌药使用减量化行动、强化兽用麻醉药品和精神药品等高风险产品监管。",null,"本网讯　近日，农业农村部在京召开兽药管理专题会议，深入学习贯彻习近平总书记重要指示精神，落实党中央、国务院决策部署，研究交流兽药产业发展和管理情况，部署下一阶段重点工作和政策举措。农业农村部党组成员、副部长张治礼出席会议并讲话。\n\n会议指出，经过多年发展，我国兽药产业逐步发展壮大，已形成较为完备的产业体系。兽药产品供给充足，质量保持较高水平，不仅有效支撑了养殖业健康发展，维护了动物产品质量安全，还助力阻断了重点人兽共患病向人间传播风险，有力保障了公共卫生安全。\n\n会议强调，推进兽药产业持续健康发展，强化全链条监管，大力推广新产品新技术，对于保障动物产品稳定安全、构建多元供给体系具有重要作用，必须锚定高质量发展目标，多措并举抓好强监管、促发展各项工作。要不断研究优化审批程序和技术要求，提高水产和宠物用兽药等注册评审效率，满足产业发展急需。注重发挥企业创新主体作用，建立健全对接服务机制，持续加大对企业创新的支持力度，加快新兽药产品上市步伐。深入开展专项整治，严肃查处违规生产、经营和使用兽药问题，会同有关部门强化兽用麻醉药品和精神药品等高风险产品监管，持续推进兽用抗菌药使用减量化行动。\n\n农业农村部畜牧兽医局、渔业渔政局及中国动物疫病预防控制中心、中国兽医药品监察所、中国水产科学研究院、全国水产技术推广总站等单位有关负责同志参会。","农业农村部新闻办公室 2026 年 10 月 15 日","2026-10-15T05:54:00Z","政策",10,false,83,{"impact":17,"substance":18,"depth":19,"authority":20,"freshness":13,"relevant":21,"comment":22},26,18,14,15,1,"全国性兽药管理政策部署会议，明确审批优化、创新支持与抗菌药减量化方向，权威性与时效性俱佳，值得进入每日精选。",[24],{"name":10,"url":6},[26,27,28,29,30],"兽药管理","抗菌药减量化","动物产品安全","宠物用兽药","全链条监管",{"code":32,"slug":33,"name":34,"path":35,"parent_code":36},"C5","animal-health","疫病防控与兽药","\u002Ftopic\u002Flivestock\u002Fanimal-health","C",[],{"status":39,"locked":14,"version":40,"method":41,"evidence":42},"classified","2026-10-22.2","rules",{"candidates":43,"agricultural_evidence":46},[44,51],{"code":32,"score":45,"supported":46,"title":47,"abstract":49,"tags":50},11,true,[48],"兽药",[48],[],{"code":52,"score":53,"supported":46,"title":54,"abstract":55,"tags":57},"D",3,[],[56],"水产",[],[59,60],"农业农村部 兽药管理 专题会议","兽用抗菌药 减量化 行动","农业农村部兽药管理专题会议-5020",0,"2026-10-16T00:13:02.051716Z",{"total":65,"page":21,"page_size":65,"items":66},6,[67,120,165,197,239,272],{"id":68,"title":69,"url":70,"summary":71,"summary_zh":8,"content":72,"source_name":73,"source_url":8,"published_at":74,"category":12,"cover_url":8,"hotness":13,"is_selected":14,"score":75,"score_detail":76,"sources":81,"tags":83,"primary_topic":88,"secondary_topics":89,"classification":96,"search_phrases":115,"slug":118,"view_count":62,"doi":8,"paper":8,"created_at":119},5417,"江西七部门合力规范农药兽药生产经营使用","https:\u002F\u002Fwww.moa.gov.cn\u002Fxw\u002Fqg\u002F202610\u002Ft20261019_6488750.htm","江西省农业农村厅等部门七部门联合部署规范农药兽药生产经营使用秩序的专项行动，从生产、经营、使用多环节切入治理。这是农业农村部推动农药兽药全链条常态化监管在地方落地的最新案例，与此前部署的规范农药兽药网络经营秩序七部门综合整治行动相衔接。对涉农经营主体而言，合规经营、索证索票与用药记录的规范化要求将持续收紧，也推动农产品质量安全智慧监管与追溯体系加速落地。","10月12日，江西省农业农村厅联合省高级人民法院、省人民检察院、省工业和信息化厅、省公安厅、省市场监管局、省供销联社等七部门召开会议，合力推动规范农药兽药生产经营使用综合整治工作取得更大成效。\n\n据了解，今年7月，农业农村部等七部门联合部署启动了进一步规范农药兽药生产经营使用综合整治行动，对禁限用农药兽药生产、经营、网售、使用等，依法开展全环节全链条整治，严打禁限用农药兽药非法生产经营使用行为。\n\n自行动启动以来，江西省积极落实国家部署要求，有序推进各项工作。目前，全省累计核查农药兽药生产经营使用主体9311家，立案查处农兽药案件73起，完成省级农药兽药及农产品质量抽检14027批次，整治经验入选全国专项简报5期，综合整治工作取得阶段性进展。\n\n当前，行动已进入提速攻坚、决战决胜的关键阶段，江西省将紧扣“打源头、端窝点、查大案”主攻方向和“端掉一批黑窝点，查获一批禁用农药兽药，清理一批违法网店，查办一批大案要案，曝光一批反面典型”五个一批目标，严格落实“必须出重拳、下狠手，打源头”三个必须要求，坚决守住全省农产品质量安全底线。（江西日报全媒体记者 李耀文）","农业农村部 2026-10-20","2026-10-20T00:00:00Z",74,{"impact":77,"substance":18,"depth":20,"authority":78,"freshness":79,"relevant":21,"comment":80},20,12,9,"省级多部门联合整治，含核查主体、立案、抽检等实质数据，属政策落地进展，值得进入每日精选。",[82],{"name":73,"url":70},[84,85,86,87],"农产品质量安全","江西","农药兽药","专项整治",{"code":32,"slug":33,"name":34,"path":35,"parent_code":36},[90],{"code":91,"slug":92,"name":93,"path":94,"parent_code":95},"F4","crop-protection","农药与绿色防控","\u002Ftopic\u002Finputs-equipment\u002Fcrop-protection","F",{"status":39,"locked":14,"version":40,"method":41,"evidence":97},{"candidates":98,"agricultural_evidence":46},[99,103,108],{"code":32,"score":45,"supported":46,"title":100,"abstract":101,"tags":102},[48],[48],[],{"code":91,"score":45,"supported":46,"title":104,"abstract":106,"tags":107},[105],"农药",[105],[],{"code":109,"score":110,"supported":46,"title":111,"abstract":112,"tags":114},"E4",4,[],[113],"农产品质量",[84],[116,117],"江西 农药兽药 综合整治","七部门 农药兽药 监管","江西农药兽药综合整治-5417","2026-10-21T00:09:54.583934Z",{"id":121,"title":122,"url":123,"summary":124,"summary_zh":8,"content":8,"source_name":125,"source_url":8,"published_at":8,"category":126,"cover_url":8,"hotness":13,"is_selected":14,"score":127,"score_detail":128,"sources":132,"tags":134,"primary_topic":140,"secondary_topics":141,"classification":142,"search_phrases":160,"slug":163,"view_count":62,"doi":8,"paper":8,"created_at":164},5342,"山东省农科院畜牧兽医所猪三联灭活疫苗获批国家新兽药(第 1062 号公告)","http:\u002F\u002Fsdxms.com\u002Farticles\u002Fch13486\u002F202610\u002F6caa12a8-303a-4162-8797-9c721b400946.shtml","山东省农业科学院畜牧兽医研究所动物疫病防控创新团队研发的猪链球菌、副猪格拉瑟菌、猪圆环病毒 2 型三联灭活疫苗(2 型 QH 株+5 型 LZ 株+Cap 蛋白)获农业农村部第 1062 号公告批准,取得国家新兽药注册证书【2026 新兽药证字 109 号】。该产品已转让三家大型动保企业,正式进入产业化落地阶段。临床上猪圆环病毒病常诱发猪链球菌、副猪格拉瑟菌的继发感染,该疫苗实现一针防三病,能显著减少免疫频次。","山东省农业科学院畜牧兽医研究所 2026-10","报道",77,{"impact":129,"substance":129,"depth":19,"authority":130,"freshness":65,"relevant":21,"comment":131},22,13,"国家级新兽药获批并进入产业化，信息具体、信源权威，对生猪疫病防控有实质产业价值，值得进入每日精选。",[133],{"name":125,"url":123},[135,136,137,138,139],"成果转化","新兽药","山东省农科院","生猪疫病防控","疫苗研发",{"code":32,"slug":33,"name":34,"path":35,"parent_code":36},[],{"status":39,"locked":14,"version":40,"method":41,"evidence":143},{"candidates":144,"agricultural_evidence":46},[145,150,155],{"code":32,"score":20,"supported":46,"title":146,"abstract":147,"tags":149},[48],[148,48],"动物疫病",[136],{"code":36,"score":45,"supported":46,"title":151,"abstract":153,"tags":154},[152],"畜牧",[152],[],{"code":156,"score":21,"supported":14,"title":157,"abstract":158,"tags":159},"G1",[],[],[135],[161,162],"猪三联灭活疫苗 新兽药","山东农科院 猪链球菌 副猪格拉瑟菌","猪三联灭活疫苗新兽药-5342","2026-10-20T02:47:43.773043Z",{"id":166,"title":167,"url":168,"summary":169,"summary_zh":8,"content":170,"source_name":171,"source_url":8,"published_at":172,"category":126,"cover_url":8,"hotness":13,"is_selected":14,"score":15,"score_detail":173,"sources":175,"tags":177,"primary_topic":183,"secondary_topics":184,"classification":185,"search_phrases":192,"slug":195,"view_count":62,"doi":8,"paper":8,"created_at":196},5338,"中国农科院哈尔滨兽医所揭示非洲猪瘟病毒与宿主攻防机制 Advanced Science","https:\u002F\u002Fnews.sciencenet.cn\u002Fhtmlnews\u002F2026\u002F10\u002F572939.shtm","中国农业科学院哈尔滨兽医研究所猪烈性传染病创新团队揭示了内质网自噬如何抑制非洲猪瘟病毒衣壳组装以及病毒如何反击的分子机制,相关研究成果发表在 Advanced Science 上。研究通过体内外实验发现,这种关键受体介导的内质网自噬能够降解非洲猪瘟病毒的衣壳蛋白,抑制衣壳组装;作为逃逸策略,非洲猪瘟病毒通过分子模拟劫持细胞自噬系统反过来降解该受体。该研究为开发新型抗病毒制剂提供了新靶标,论文 DOI: 10.1002\u002Fadvs.77741。","[![Image 1: 科学网新闻频道](https:\u002F\u002Fnews.sciencenet.cn\u002Fimages\u002Fnews.jpg)](https:\u002F\u002Fnews.sciencenet.cn\u002F)\n\n[生命科学](https:\u002F\u002Fwww.sciencenet.cn\u002Flife\u002F) | [医学科学](https:\u002F\u002Fwww.sciencenet.cn\u002Fmedicine\u002F) | [化学科学](https:\u002F\u002Fwww.sciencenet.cn\u002Fchemistry\u002F) | [工程材料](https:\u002F\u002Fwww.sciencenet.cn\u002Fmaterial\u002F) | [信息科学](https:\u002F\u002Fwww.sciencenet.cn\u002Finformation\u002F) | [地球科学](https:\u002F\u002Fwww.sciencenet.cn\u002Fearth\u002F) | [数理科学](https:\u002F\u002Fwww.sciencenet.cn\u002Fmathematics\u002F) | [管理综合](https:\u002F\u002Fwww.sciencenet.cn\u002Fpolicy\u002F)[站内规定](https:\u002F\u002Fblog.sciencenet.cn\u002Fblog-45-1064777.html) | [手机版](https:\u002F\u002Fwap.sciencenet.cn\u002F)\n\n[首页](https:\u002F\u002Fwww.sciencenet.cn\u002F) | [新闻](https:\u002F\u002Fnews.sciencenet.cn\u002F) | [博客](https:\u002F\u002Fblog.sciencenet.cn\u002Fblog.php) | [院士](https:\u002F\u002Fnews.sciencenet.cn\u002Fys\u002F) | [人才](https:\u002F\u002Ftalent.sciencenet.cn\u002F) | [会议](https:\u002F\u002Fmeeting.sciencenet.cn\u002F) | [基金·项目](https:\u002F\u002Ffund.sciencenet.cn\u002F) | [论文](https:\u002F\u002Fpaper.sciencenet.cn\u002F) | [绘图](https:\u002F\u002Fvisual-web.sciencenet.cn\u002F) | [视频·直播](https:\u002F\u002Fblog.sciencenet.cn\u002Fblog.php?mod=video) | [小柯机器人](https:\u002F\u002Fpaper.sciencenet.cn\u002FAInews) | [医学科普](https:\u002F\u002Fyxkp.sciencenet.cn\u002F)\n\n作者：李晨,邓彦莉 来源：中国科学报 发布时间：2026\u002F10\u002F15 11:58:32 选择字号：小 中 大 研究揭示非洲猪瘟病毒与宿主“攻防”机制 近日，中国农业科学院哈尔滨兽医研究所猪烈性传染病创新团队揭示了内质网自噬如何抑制非洲猪瘟病毒衣壳组装，以及病毒如何“反击”的分子机制。相关研究成果发表在《先进科学》（_**Advanced Science**_）上。 内质网如同蛋白质的生产“车间”。当受损或多余蛋白质出现时，细胞会启动内质网自噬进行清理，这一过程由关键受体分子负责。 该研究通过体内外实验发现，这种关键受体介导的内质网自噬能够降解非洲猪瘟病毒的衣壳蛋白，抑制衣壳组装，从而发挥抗病毒功能。作为逃逸策略，非洲猪瘟病毒则通过“分子模拟”劫持细胞自噬系统，反过来降解该受体，从而拮抗其抗病毒功能。 该研究为拓展非洲猪瘟病毒与宿主相互博弈的认知及开发新型抗病毒制剂提供了新靶标。研究得到国家自然科学基金、黑龙江省自然科学基金和中国农业科学院青年创新专项等项目支持。 相关论文信息：https:\u002F\u002Fdoi.org\u002F10.1002\u002Fadvs.77741 版权声明：凡本网注明“来源：中国科学报、科学网、科学新闻杂志”的所有作品，网站转载，请在正文上方注明来源和作者，且不得对内容作实质性改动；微信公众号、头条号等新媒体平台，转载请联系授权。邮箱：shouquan@stimes.cn。\n\n打印 发E-mail给：\n\n以下评论只代表网友个人观点，不代表科学网观点。\n\n[![Image 2](https:\u002F\u002Fnews.sciencenet.cn\u002Fimages\u002Fnewcomm.gif)](https:\u002F\u002Fnews.sciencenet.cn\u002Fhtml\u002Fcomment.aspx?id=572939)\n\n相关新闻 相关论文\n*   1\n*   [微型机器人靶向心脏感染病灶精准送药](https:\u002F\u002Fnews.sciencenet.cn\u002Fhtmlnews\u002F2026\u002F10\u002F572918.shtm)\n\n*   2\n*   [这个打破常识的发现因何而来](https:\u002F\u002Fnews.sciencenet.cn\u002Fhtmlnews\u002F2026\u002F10\u002F572917.shtm)\n\n*   3\n*   [科学家捕获最远快速射电暴](https:\u002F\u002Fnews.sciencenet.cn\u002Fhtmlnews\u002F2026\u002F10\u002F572916.shtm)\n\n*   4\n*   [罗先刚院士：科技创新下一程，不是“接力赛”！](https:\u002F\u002Fnews.sciencenet.cn\u002Fhtmlnews\u002F2026\u002F10\u002F572915.shtm)\n\n*   5\n*   [研究显示：孕期慢性压力会改变胎盘影响胎儿大脑发育](https:\u002F\u002Fnews.sciencenet.cn\u002Fhtmlnews\u002F2026\u002F10\u002F572914.shtm)\n\n*   6\n*   [冲刺顶刊，中国科技期刊还有多远](https:\u002F\u002Fnews.sciencenet.cn\u002Fhtmlnews\u002F2026\u002F10\u002F572913.shtm)\n\n*   7\n*   [打破传统认知，1.5亿年前的“神鸟”不会飞](https:\u002F\u002Fnews.sciencenet.cn\u002Fhtmlnews\u002F2026\u002F10\u002F572912.shtm)\n\n*   8\n*   [科技部国际合作司发布1个项目征集通知](https:\u002F\u002Fnews.sciencenet.cn\u002Fhtmlnews\u002F2026\u002F10\u002F572907.shtm)\n\n*   1\n*   [Angew 原位EPR揭示共价有机框架储钠过程中的自由基演变机制](https:\u002F\u002Fnews.sciencenet.cn\u002Fhtmlpaper\u002F2026\u002F10\u002F2026101511329599156545.shtm)\n\n*   2\n*   [浙江大学李斌研究员Angew：多元功能化MOF策略精准调控水吸附\u002F脱附性能实现吸附式制冷性能突破](https:\u002F\u002Fnews.sciencenet.cn\u002Fhtmlpaper\u002F2026\u002F10\u002F202610151127850156544.shtm)\n\n*   3\n*   [上海有机化学研究所王鹏团队Angew：镍催化多类型联烯的不对称氢硅化反应](https:\u002F\u002Fnews.sciencenet.cn\u002Fhtmlpaper\u002F2026\u002F10\u002F2026101510336599156543.shtm)\n\n*   4\n*   [苏州纳米所王强斌，埃默里大学柯勇刚课题组 Angew: DNA支架实现对称蛋白组装体的位点选择性编辑](https:\u002F\u002Fnews.sciencenet.cn\u002Fhtmlpaper\u002F2026\u002F10\u002F20261015102739193156542.shtm)\n\n*   5\n*   [东北师范大学吴兴隆Angew:双域耦合驱动的界面重塑助力超低浓度的阻燃电解液用于高电压宽温域电池](https:\u002F\u002Fnews.sciencenet.cn\u002Fhtmlpaper\u002F2026\u002F10\u002F2026101510275458156541.shtm)\n\n*   6\n*   [上海大学张志坤团队Angew：CF2H(D)苯并咪唑盐实现烯烃双二氟（氘）甲基化](https:\u002F\u002Fnews.sciencenet.cn\u002Fhtmlpaper\u002F2026\u002F10\u002F2026101510251168156540.shtm)\n\n*   7\n*   [OEA丨告别“海量数据”训练！物理感知神经网络为散斑重建光谱仪打造自适应“大脑”](https:\u002F\u002Fnews.sciencenet.cn\u002Fhtmlpaper\u002F2026\u002F10\u002F2026101573325411156539.shtm)\n\n*   8\n*   [Applied Mechanics：航空航天系统的结构动力学和实验力学 | MDPI 特刊征稿](https:\u002F\u002Fnews.sciencenet.cn\u002Fhtmlpaper\u002F2026\u002F10\u002F2026101415211693156537.shtm)\n\n[图片新闻](https:\u002F\u002Fnews.sciencenet.cn\u002Fimgnews.aspx)\n\n[![Image 3: 一串红新品种亮相长安街花坛](https:\u002F\u002Fnews.sciencenet.cn\u002F\u002Fupload\u002Fnews\u002Fimages\u002F2026\u002F10\u002F202610151335227710.jpg)](https:\u002F\u002Fnews.sciencenet.cn\u002Fhttps:\u002F\u002Fnews.sciencenet.cn\u002Fhtmlnews\u002F2026\u002F10\u002F572943.shtm)[![Image 4: 在原子尺度“观察”交错磁序](https:\u002F\u002Fnews.sciencenet.cn\u002F\u002Fupload\u002Fnews\u002Fimages\u002F2026\u002F10\u002F20261014113318990.png)](https:\u002F\u002Fnews.sciencenet.cn\u002Fhttps:\u002F\u002Fnews.sciencenet.cn\u002Fhtmlnews\u002F2026\u002F10\u002F572860.shtm)\n[![Image 5: 打通试验田到生产田的“最后一公里”](https:\u002F\u002Fnews.sciencenet.cn\u002F\u002Fupload\u002Fnews\u002Fimages\u002F2026\u002F10\u002F202610121054457860.jpg)](https:\u002F\u002Fnews.sciencenet.cn\u002Fhttps:\u002F\u002Fnews.sciencenet.cn\u002Fhtmlnews\u002F2026\u002F10\u002F572770.shtm)[![Image 6: 科学网2026年9月十佳博文榜单公布！](https:\u002F\u002Fnews.sciencenet.cn\u002F\u002Fupload\u002Fnews\u002Fimages\u002F2026\u002F10\u002F202610101238573490.jpg)](https:\u002F\u002Fnews.sciencenet.cn\u002Fhttps:\u002F\u002Fblog.sciencenet.cn\u002Fblog-45-1555866.html)\n[>>更多](https:\u002F\u002Fnews.sciencenet.cn\u002Fimgnews.aspx)\n\n[一周新闻排行](https:\u002F\u002Fnews.sciencenet.cn\u002Fzphnews.aspx)\n*   1\n*   [香港中文大学（深圳）教授李仁科出席会议期间辞世](https:\u002F\u002Fnews.sciencenet.cn\u002F\u002Fhtmlnews\u002F2026\u002F10\u002F572870.shtm)\n\n*   2\n*   [教师举报自己论文两次被同事冒用](https:\u002F\u002Fnews.sciencenet.cn\u002F\u002Fhtmlnews\u002F2026\u002F10\u002F573051.shtm)\n\n*   3\n*   [自掏工资悬赏解题！这位教授提了上千个猜想](https:\u002F\u002Fnews.sciencenet.cn\u002F\u002Fhtmlnews\u002F2026\u002F10\u002F572906.shtm)\n\n*   4\n*   [华裔工程师投毒加害同门，申请消除犯罪记录竟获批准](https:\u002F\u002Fnews.sciencenet.cn\u002F\u002Fhtmlnews\u002F2026\u002F10\u002F572853.shtm)\n\n*   5\n*   [2026年高等教育国家教学成果奖申报项目公示](https:\u002F\u002Fnews.sciencenet.cn\u002F\u002Fhtmlnews\u002F2026\u002F10\u002F572829.shtm)\n\n*   6\n*   [连续4年空缺的国自然科学一等奖，被他们拿下](https:\u002F\u002Fnews.sciencenet.cn\u002F\u002Fhtmlnews\u002F2026\u002F10\u002F572869.shtm)\n\n*   7\n*   [北大物理学理论物理研究所教授卢大海逝世，享年82岁](https:\u002F\u002Fnews.sciencenet.cn\u002F\u002Fhtmlnews\u002F2026\u002F10\u002F572866.shtm)\n\n*   8\n*   [把拓扑材料做成探针 在原子尺度“观察”交错磁序](https:\u002F\u002Fnews.sciencenet.cn\u002F\u002Fhtmlnews\u002F2026\u002F10\u002F572860.shtm)\n\n*   9\n*   [吴军全职加入西湖大学](https:\u002F\u002Fnews.sciencenet.cn\u002F\u002Fhtmlnews\u002F2026\u002F10\u002F572879.shtm)\n\n*   10\n*   [微型机器人靶向心脏感染病灶精准送药](https:\u002F\u002Fnews.sciencenet.cn\u002F\u002Fhtmlnews\u002F2026\u002F10\u002F572918.shtm)\n\n[编辑部推荐博文](http:\u002F\u002Fblog.sciencenet.cn\u002Fblog.php?mod=recommend)\n*   ![Image 7](https:\u002F\u002Fnews.sciencenet.cn\u002Fimages\u002Ft11.gif)\n*   [封面文章 | hLife：设计新型呼吸道病毒黏膜疫苗](https:\u002F\u002Fblog.sciencenet.cn\u002Fblog-45-1556586.html)\n\n*   ![Image 8](https:\u002F\u002Fnews.sciencenet.cn\u002Fimages\u002Ft11.gif)\n*   [科学网2026年9月十佳博文榜单公布！](https:\u002F\u002Fblog.sciencenet.cn\u002Fblog-45-1555866.html)\n\n*   ![Image 9](https:\u002F\u002Fnews.sciencenet.cn\u002Fimages\u002Ft11.gif)\n*   [杂说粮食（6）玉米与高粱](https:\u002F\u002Fblog.sciencenet.cn\u002Fblog-612874-1557355.html)\n\n*   ![Image 10](https:\u002F\u002Fnews.sciencenet.cn\u002Fimages\u002Ft11.gif)\n*   [“耐心”是突破性创新的必要土壤](https:\u002F\u002Fblog.sciencenet.cn\u002Fblog-1251036-1557352.html)\n\n*   ![Image 11](https:\u002F\u002Fnews.sciencenet.cn\u002Fimages\u002Ft11.gif)\n*   [学历“面子”与生存“里子”：学位选择的终极逻辑](https:\u002F\u002Fblog.sciencenet.cn\u002Fblog-3316383-1557345.html)\n\n*   ![Image 12](https:\u002F\u002Fnews.sciencenet.cn\u002Fimages\u002Ft11.gif)\n*   [如何面对基金申请落选](https:\u002F\u002Fblog.sciencenet.cn\u002Fblog-729911-1557142.html)\n\n*   [更多>>](https:\u002F\u002Fblog.sciencenet.cn\u002Fblog.php?mod=recommend)\n\n* * *\n\n近日，中国农业科学院哈尔滨兽医研究所猪烈性传染病创新团队揭示了内质网自噬如何抑制非洲猪瘟病毒衣壳组装，以及病毒如何“反击”的分子机制。相关研究成果发表在《先进科学》（_**Advanced Science**_）上。\n\n内质网如同蛋白质的生产“车间”。当受损或多余蛋白质出现时，细胞会启动内质网自噬进行清理，这一过程由关键受体分子负责。\n\n该研究通过体内外实验发现，这种关键受体介导的内质网自噬能够降解非洲猪瘟病毒的衣壳蛋白，抑制衣壳组装，从而发挥抗病毒功能。作为逃逸策略，非洲猪瘟病毒则通过“分子模拟”劫持细胞自噬系统，反过来降解该受体，从而拮抗其抗病毒功能。\n\n该研究为拓展非洲猪瘟病毒与宿主相互博弈的认知及开发新型抗病毒制剂提供了新靶标。研究得到国家自然科学基金、黑龙江省自然科学基金和中国农业科学院青年创新专项等项目支持。\n\n相关论文信息：https:\u002F\u002Fdoi.org\u002F10.1002\u002Fadvs.77741","中国农业科学院哈尔滨兽医研究所 2026-10-15","2026-10-15T00:00:00Z",{"impact":129,"substance":129,"depth":18,"authority":20,"freshness":65,"relevant":21,"comment":174},"国家级科研机构在顶刊发表非洲猪瘟攻防机制新发现，为新型抗病毒制剂提供靶标，专业增量明确，但属基础研究、时效稍弱，可入精选。",[176],{"name":171,"url":168},[178,179,180,181,182],"动物疫病防控","非洲猪瘟","内质网自噬","病毒与宿主互作","抗病毒靶标",{"code":32,"slug":33,"name":34,"path":35,"parent_code":36},[],{"status":39,"locked":14,"version":40,"method":41,"evidence":186},{"candidates":187,"agricultural_evidence":46},[188],{"code":32,"score":130,"supported":46,"title":189,"abstract":190,"tags":191},[179],[179],[178,179],[193,194],"哈兽研 非洲猪瘟 衣壳组装","非洲猪瘟病毒 内质网自噬","哈兽研非洲猪瘟衣壳组装-5338","2026-10-20T02:47:43.543999Z",{"id":198,"title":199,"url":200,"summary":201,"summary_zh":8,"content":202,"source_name":203,"source_url":8,"published_at":8,"category":126,"cover_url":8,"hotness":13,"is_selected":46,"score":204,"score_detail":205,"sources":209,"tags":211,"primary_topic":216,"secondary_topics":217,"classification":218,"search_phrases":234,"slug":237,"view_count":21,"doi":8,"paper":8,"created_at":238},5214,"山东省农科院首创猪链球菌-副猪格拉瑟菌-猪圆环病毒2型三联灭活疫苗获国家新兽药","http:\u002F\u002Fwww.saas.ac.cn\u002Farticles\u002Fch10721\u002F202610\u002F3363f4c1-7d36-4c1b-a996-f5ec3bab1b34.shtml","山东省农业科学院畜牧兽医所动物疫病防控创新团队研发的猪链球菌、副猪格拉瑟菌、猪圆环病毒2型三联灭活疫苗获农业农村部批准国家新兽药注册证书(【2026】新兽药证字109号),实现\"一针防三病\"。","近日，农业农村部发布第1062号公告，畜牧兽医所动物疫病防控创新团队研发的“猪链球菌、副猪格拉瑟菌、猪圆环病毒2型三联灭活疫苗(2型QH株+5型LZ株+Cap蛋白)”获农业农村部批准，取得国家新兽药注册证书（【2026】新兽药证字109号），标志着我院在猪多联多价疫苗研发领域实现重要突破。\n\n临床上，猪圆环病毒病常诱发猪链球菌、副猪格拉瑟菌的继发感染，导致猪群死淘率升高，已成为制约养猪业健康发展的突出痛点。畜牧兽医研究所动物疫病防控创新团队针对生猪病毒和细菌混合感染高发、免疫程序繁杂等产业难题持续攻关，突破细菌高密度精准发酵、蛋白高效表达纯化、多抗原协同兼容等关键技术瓶颈，自主创制出国内外首个猪链球菌、副猪格拉瑟菌、猪圆环病毒2型三联灭活疫苗，实现“一针防三病”，能显著减少免疫频次，降低养殖防疫成本和猪群应激。目前，该产品已转让三家大型动保企业，正式进入产业化落地的重要阶段。产品量产落地后，将补齐生猪混合感染疫病高效防控短板，助推生猪养殖业稳产提质、健康可持续发展。（撰稿：于江     核稿：朱小玲）","山东省农业科学院(2026-10)",88,{"impact":17,"substance":206,"depth":207,"authority":19,"freshness":79,"relevant":21,"comment":208},23,16,"国内首个猪用三联灭活疫苗获国家新兽药证书并进入产业化，属产业级技术突破，信息增量与信源权威度俱佳，值得进入每日精选。",[210],{"name":203,"url":200},[136,212,213,214,215],"生猪养殖","疫病防控","兽药疫苗","科研成果",{"code":32,"slug":33,"name":34,"path":35,"parent_code":36},[],{"status":39,"locked":14,"version":40,"method":41,"evidence":219},{"candidates":220,"agricultural_evidence":46},[221,225,229],{"code":32,"score":20,"supported":46,"title":222,"abstract":223,"tags":224},[48],[148,48],[136],{"code":36,"score":53,"supported":46,"title":226,"abstract":227,"tags":228},[],[152],[],{"code":230,"score":21,"supported":14,"title":231,"abstract":232,"tags":233},"C1",[],[],[212],[235,236],"山东省农科院 猪链球菌 三联灭活疫苗","猪圆环病毒2型 新兽药 证书","山东省农科院猪链球菌三联灭活疫苗-5214","2026-10-18T00:05:23.181714Z",{"id":240,"title":241,"url":242,"summary":243,"summary_zh":8,"content":244,"source_name":245,"source_url":8,"published_at":246,"category":126,"cover_url":8,"hotness":13,"is_selected":14,"score":15,"score_detail":247,"sources":249,"tags":251,"primary_topic":254,"secondary_topics":255,"classification":256,"search_phrases":267,"slug":270,"view_count":62,"doi":8,"paper":8,"created_at":271},5209,"中国农科院哈尔滨兽医所揭示非洲猪瘟病毒与宿主\"攻防\"新机制","https:\u002F\u002Fhvri.caas.cn\u002Fxwzh\u002Fmtbd\u002F8445b415e6c8458a9754862c223d45eb.htm","中国农业科学院哈尔滨兽医研究所揭示内质网自噬如何抑制非洲猪瘟病毒衣壳组装及病毒如何\"反击\"的分子机制,研究发现病毒通过分子模拟劫持细胞自噬系统,拮抗受体抗病毒功能,为开发新型抗病毒制剂提供新靶标,研究成果发表于《Advanced Science》。","近日，中国农业科学院哈尔滨兽医研究所猪烈性传染病创新团队揭示了内质网自噬如何抑制非洲猪瘟病毒衣壳组装，以及病毒如何“反击”的分子机制。相关研究成果发表在《先进科学（Advanced Science）》上。\n\n内质网如同蛋白质的生产“车间”。当受损或多余蛋白质出现时，细胞会启动内质网自噬进行清理，这一过程由关键受体分子负责。该研究通过体内外实验发现，这种关键受体介导的内质网自噬能够降解非洲猪瘟病毒的衣壳蛋白，抑制衣壳组装，从而发挥抗病毒功能。作为逃逸策略，非洲猪瘟病毒则通过“分子模拟”劫持细胞自噬系统，反过来降解该受体，从而拮抗其抗病毒功能。该研究为拓展非洲猪瘟病毒与宿主相互博弈的认知及开发新型抗病毒制剂提供了新靶标。\n\n该研究得到国家自然科学基金、黑龙江省自然科学基金和中国农业科学院青年创新专项等项目支持。（通讯员 邓彦莉）","中国农业科学院哈尔滨兽医所(2026-10-12)","2026-10-12T00:00:00Z",{"impact":129,"substance":129,"depth":18,"authority":20,"freshness":65,"relevant":21,"comment":248},"国家级科研机构在非洲猪瘟基础研究上取得新机制发现，专业增量明确，对生猪疫病防控有潜在价值，值得进入每日精选。",[250],{"name":245,"url":242},[178,179,212,252,253],"病毒学","抗病毒制剂",{"code":32,"slug":33,"name":34,"path":35,"parent_code":36},[],{"status":39,"locked":14,"version":40,"method":41,"evidence":257},{"candidates":258,"agricultural_evidence":46},[259,263],{"code":32,"score":130,"supported":46,"title":260,"abstract":261,"tags":262},[179],[179],[178,179],{"code":230,"score":21,"supported":14,"title":264,"abstract":265,"tags":266},[],[],[212],[268,269],"哈尔滨兽医所 非洲猪瘟 衣壳组装","非洲猪瘟 内质网自噬 分子机制","哈尔滨兽医所非洲猪瘟衣壳组装-5209","2026-10-18T00:05:22.874379Z",{"id":273,"title":274,"url":275,"summary":276,"summary_zh":8,"content":277,"source_name":278,"source_url":8,"published_at":172,"category":12,"cover_url":8,"hotness":13,"is_selected":46,"score":279,"score_detail":280,"sources":286,"tags":288,"primary_topic":293,"secondary_topics":294,"classification":295,"search_phrases":307,"slug":310,"view_count":62,"doi":8,"paper":8,"created_at":311},5196,"中华人民共和国农业农村部公告 第1073号","https:\u002F\u002Fwww.moa.gov.cn\u002Fgovpublic\u002Fxmsyj\u002F202610\u002Ft20261016_6488649.htm","2026年10月15日农业农村部发布公告,自《中国兽药典(第七版)》三部公布之日起实施,2027年5月1日起申报兽用生物制品批准文号应按符合新版兽药典要求的、经核准的兽药注册标准进行样品检验,进一步规范兽药质量控制,提升行业监管水平。","根据《兽药管理条例》规定，我部组织完成《中华人民共和国兽药典（第七版）》（以下简称《中国兽药典（第七版）》）三部的编制工作，现予发布，自2027年5月1日起施行。现就有关事宜公告如下。\n\n一、《中华人民共和国兽药典》是兽药研制、生产（进口）、经营、使用和监督管理活动应遵循的法定技术标准。\n\n二、《中国兽药典（第七版）》三部收载兽用生物制品，包括凡例、品种正文和附录。其中，品种正文属于通用标准，是基于单一抗原制定的、适用于同类制品的兽药国家标准。\n\n三、自施行之日起，《中国兽药典（第七版）》三部未收载且未公布废止的品种标准，包括历版《中华人民共和国兽药典》三部、《兽药质量标准（2017年版）》生物制品卷、《中国兽用生物制品规程（2000年版）》收载的产品标准仍继续有效，但应符合《中国兽药典（第七版）》三部相关通用要求。\n\n《中国兽药典（第七版）》三部施行之日前，相关产品生产企业应及时开展标准对比研究工作，评估兽药注册标准是否符合《中国兽药典（第七版）》三部有关要求，并根据需要履行相关标准变更程序（见附件）。\n\n四、2027年5月1日起生产的有关兽药产品应同时符合《中国兽药典（第七版）》三部要求和经农业农村部核准的兽药注册标准。2027年4月30日（含）前生产的有关兽药产品可按原兽药质量标准进行检验，并在产品有效期内流通使用。\n\n五、2027年5月1日起申报兽用生物制品新兽药注册和进口兽药注册的，应符合《中国兽药典（第七版）》三部要求。\n\n六、2027年5月1日起申报兽用生物制品批准文号的，应按照符合《中国兽药典（第七版）》三部要求的、经农业农村部核准的兽药注册标准进行样品检验。换发兽药产品批准文号的，应提供符合《中国兽药典（第七版）》三部要求的技术文件。2027年4月30日（含）前申报的，兽药检验报告的执行标准可为原兽药注册标准，也可为符合《中国兽药典（第七版）》三部有关要求、经农业农村部新核准的兽药注册标准。\n\n七、各级畜牧兽医主管部门要积极做好《中国兽药典（第七版）》三部宣传贯彻和实施工作，收集和反馈相关问题和意见。中国兽药典委员会办公室应及时答复各地反映的有关问题，做好技术指导、标准勘误等工作。\n\n八、各兽药企业要认真执行《中国兽药典（第七版）》三部，不断提高兽药产品质量控制水平。","农业农村部(2026-10-15)",94,{"impact":281,"substance":282,"depth":283,"authority":20,"freshness":284,"relevant":21,"comment":285},28,24,19,8,"农业农村部发布第七版兽药典三部，属全国性兽药法定技术标准更新，条款与过渡安排具体，权威性和信息增量高，值得进入每日精选。",[287],{"name":278,"url":275},[289,290,291,292],"行业标准","兽药典","兽药监管","兽用生物制品",{"code":32,"slug":33,"name":34,"path":35,"parent_code":36},[],{"status":39,"locked":14,"version":40,"method":41,"evidence":296},{"candidates":297,"agricultural_evidence":46},[298,302],{"code":32,"score":110,"supported":46,"title":299,"abstract":300,"tags":301},[],[48],[291],{"code":303,"score":21,"supported":14,"title":304,"abstract":305,"tags":306},"J1",[],[],[289],[308,309],"中国兽药典 第七版 三部","兽用生物制品 国家标准","中国兽药典第七版三部-5196","2026-10-18T00:05:13.276915Z"]