[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"item-5114":3,"related-5114":51},{"id":4,"title":5,"url":6,"summary":7,"summary_zh":8,"content":9,"source_name":10,"source_url":8,"published_at":11,"category":12,"cover_url":8,"hotness":13,"is_selected":14,"score":15,"score_detail":16,"sources":22,"tags":24,"primary_topic":8,"secondary_topics":30,"classification":31,"search_phrases":45,"slug":48,"view_count":49,"doi":8,"paper":8,"created_at":50},5114,"中国农科院上海兽医所弓形虫多表位DNA疫苗研发取得新进展","https:\u002F\u002Fwww.toutiao.com\u002Farticle\u002F7697065122149204530","中国农业科学院上海兽医研究所动物寄生虫与生物媒介控制团队利用生物信息学技术设计了一种覆盖弓形虫不同生活史阶段的多表位DNA疫苗(MEP1),并在BALB\u002Fc小鼠模型中验证了其免疫原性与保护效果,相关研究成果发表于《Frontiers in Immunology》。研究从ToxoDB数据库筛选弓形虫速殖子、缓殖子、卵囊等不同发育阶段的6个保守抗原蛋白,通过免疫信息学工具预测并筛选获得12个B细胞表位、16个HTL表位和13个CTL表位,利用特异性连接子连接后引入PADRE辅助表位,成功构建了多表位疫苗MEP1。在BALB\u002Fc小鼠模型中MEP1-pcDNA3.1免疫组血清IFN-γ水平显著升高,脾细胞增殖能力显著增强,攻毒实验免疫组小鼠生存期显著延长。",null,"## 科研动态 | 上兽研在弓形虫多表位疫苗研发中取得新进展\n\n近日，中国农业科学院上海兽医研究所动物寄生虫与生物媒介控制团队利用生物信息学技术设计了一种覆盖弓形虫不同生活史阶段的多表位DNA疫苗（MEP1），并在小鼠模型中验证了其免疫原性与保护效果。相关研究成果发表于《Frontiers in Immunology》。\n\n弓形虫（Toxoplasma gondii）是一种全球性人兽共患寄生虫，可感染人类及多种温血动物，对孕妇、胎儿及免疫功能低下人群危害尤为严重，目前尚无获批的人用疫苗。现有DNA疫苗、亚单位疫苗和减毒活疫苗均存在免疫原性不足、安全性或稳定性等局限。近年来，生物信息学和免疫信息学的发展推动了多表位疫苗设计，可精准筛选高免疫原性抗原表位，提高疫苗的安全性和免疫保护潜力，为弓形虫疫苗研发提供新的策略。\n\n本研究从ToxoDB数据库中筛选了弓形虫速殖子、缓殖子、卵囊等不同发育阶段的6个保守抗原蛋白，通过免疫信息学工具预测并筛选获得12个B细胞表位、16个HTL表位和13个CTL表位，利用特异性连接子连接后引入PADRE辅助表位，成功构建了多表位疫苗MEP1。理化性质和结构分析显示，MEP1具有稳定的构象和良好的抗原性。分子对接与免疫模拟预测表明，MEP1能与TLR4稳定结合，并有效激活B细胞、T细胞及IFN-γ应答。为验证疫苗效力，研究团队将MEP1基因克隆至pcDNA3.1载体并在HEK293T细胞中成功表达。在BALB\u002Fc小鼠模型中，MEP1-pcDNA3.1免疫组血清IFN-γ水平显著升高，脾细胞增殖能力显著增强。攻毒实验中，免疫组小鼠生存期显著延长，心脏、肝脏、脾脏、肺脏、脑等组织荷虫量均显著低于对照组。本研究完成了从计算机辅助设计到体内外实验验证的完整研究链条，为弓形虫疫苗研发提供了新策略，也推动了新型疫苗从计算机模拟走向实际应用。\n\n中国农业科学院上海兽医研究所与延边大学联合培养硕士研究生冯文勇为论文第一作者，上海兽医研究所张厚双研究员和延边大学于龙政副教授为论文共同通信作者。研究工作得到了国家重点研发计划项目和国家自然科学基金的资助。\n\n![Image 1](https:\u002F\u002Fp3-sign.toutiaoimg.com\u002Ftos-cn-i-axegupay5k\u002F15a66fe10ea34daca3910919e0cc8bda~tplv-tt-origin-web:gif.jpeg?_iz=58558&from=article.pc_detail&lk3s=953192f4&x-expires=1792800862&x-signature=JDU5kPXhWjr45FvWohi1BKWhTxc%3D)\n\n来源：中国农业科学院上海兽医研究所官网","中国农业科学院上海兽医研究所 今日头条 2026 年 10 月 16 日","2026-10-16T00:00:00Z","报道",10,false,82,{"impact":17,"substance":18,"depth":17,"authority":19,"freshness":13,"relevant":20,"comment":21},18,22,14,1,"国家级科研机构在弓形虫多表位DNA疫苗上完成从计算设计到小鼠攻毒验证的完整链条，方法新颖、数据扎实，具行业参考价值。",[23],{"name":10,"url":6},[25,26,27,28,29],"动物疫苗","生物信息学","人兽共患病","弓形虫","DNA疫苗",[],{"status":32,"locked":14,"version":33,"method":34,"evidence":35},"unclassified","2026-10-22.2","rules",{"candidates":36,"agricultural_evidence":43,"reason":44},[37],{"code":38,"score":39,"supported":14,"title":40,"abstract":41,"tags":42},"C5",2,[],[],[27,25],true,"缺少足够的主题证据",[46,47],"上海兽医所 弓形虫 多表位疫苗","弓形虫 DNA疫苗 MEP1","上海兽医所弓形虫多表位疫苗-5114",0,"2026-10-17T00:13:39.459666Z",{"total":52,"page":20,"page_size":52,"items":53},6,[54,129,191,232,322,365],{"id":55,"title":56,"url":57,"summary":58,"summary_zh":59,"content":8,"source_name":60,"source_url":57,"published_at":61,"category":62,"cover_url":8,"hotness":13,"is_selected":14,"score":63,"score_detail":64,"sources":68,"tags":70,"primary_topic":75,"secondary_topics":80,"classification":81,"search_phrases":106,"slug":109,"view_count":49,"doi":110,"paper":111,"created_at":128},4508,"Analyzing Bunyaviruses from a One Health Perspective","https:\u002F\u002Fdoi.org\u002F10.3390\u002Fv18101110","Zoonotic viral diseases continue to pose major challenges to global health, particularly as environmental, social and economic changes increasingly influence interactions among humans, animals, vectors, and ecosystems. This review explores Rift Valley fever virus (RVFV), Crimean-Congo hemorrhagic fever virus (CCHFV), and hantaviruses (HTVs) within the framework of One Health, emphasizing the ecological and epidemiological factors that govern their emergence and transmission. Despite their distinct transmission cycles, these viruses share important determinants of zoonotic risk. RVFV is primarily maintained through interactions between mosquitoes, livestock, wildlife, and humans; CCHFV is sustained within complex tick–vertebrate systems involving Hyalomma ticks, domestic animals, and wildlife, while HTVs are predominantly maintained through persistent infections in mammalian reservoir hosts, particularly rodents. Climate variability, habitat alteration, agricultural expansion, livestock movement, urbanization, and other anthropogenic pressures can modify these transmission systems and create new opportunities for pathogen spillover. Effective prevention and control therefore require integrated surveillance that encompasses human disease, animal populations, vectors or wildlife reservoirs, and environmental conditions. Advances in molecular diagnostics, genomic epidemiology, ecological modeling, remote sensing, and climate-based forecasting provide valuable opportunities for improving early detection and outbreak preparedness. To reduce the burden of these zoonotic viral diseases, a sustained collaboration among human and veterinary health professionals, ecologists, entomologists, environmental scientists, and public health authorities is required. Therefore, a coordinated One Health approach is essential for anticipating emerging threats, strengthening preparedness, and protecting human, animal, and ecosystem health.","人兽共患病毒病持续对全球健康构成重大挑战，尤其是当环境、社会和经济变化日益影响人类、动物、媒介和生态系统之间的相互作用时。本综述在“同一健康”（One Health）框架下探讨了裂谷热病毒（RVFV）、克里米亚-刚果出血热病毒（CCHFV）和汉坦病毒（HTVs），重点关注决定其出现和传播的生态学与流行病学因素。尽管这些病毒的传播循环各具特点，但它们共享重要的人兽共患风险决定因素。RVFV主要通过蚊、家畜、野生动物和人类之间的相互作用维持传播；CCHFV在涉及璃眼蜱属蜱、家养动物和野生动物的复杂蜱-脊椎动物系统中持续循环；而HTVs主要通过哺乳动物储存宿主（尤其是啮齿动物）的持续性感染维持。气候变异性、栖息地改变、农业扩张、家畜流动、城市化及其他人为压力可改变这些传播系统，并为病原体外溢创造新的机会。因此，有效的预防和控制需要涵盖人类疾病、动物种群、媒介或野生动物储存宿主以及环境条件的综合监测。分子诊断、基因组流行病学、生态建模、遥感和基于气候的预测等方面的进步为改善早期发现和疫情准备提供了宝贵机遇。为减轻这些人兽共患病毒病的负担，需要人类与兽医卫生专业人员、生态学家、昆虫学家、环境科学家和公共卫生当局之间的持续合作。因此，协调的“同一健康”方法对于预判新发威胁、加强防范以及保护人类、动物和生态系统健康至关重要。","Viruses","2026-10-08T00:00:00Z","论文",78,{"impact":17,"substance":65,"depth":17,"authority":19,"freshness":66,"relevant":20,"comment":67},20,8,"从One Health视角系统综述三种人兽共患病毒病的生态流行与一体化监测防控，对动物疫病预警和农业公共卫生信息化有参考价值。",[69],{"name":60,"url":57},[71,72,27,73,74],"动物疫病防控","One Health","气候与疫病","分子诊断",{"code":38,"slug":76,"name":77,"path":78,"parent_code":79},"animal-health","疫病防控与兽药","\u002Ftopic\u002Flivestock\u002Fanimal-health","C",[],{"status":82,"locked":14,"version":33,"method":34,"evidence":83},"classified",{"candidates":84,"agricultural_evidence":43},[85,93,100],{"code":38,"score":86,"supported":43,"title":87,"abstract":88,"tags":92},12,[],[89,90,91],"人兽共患","veterinary","zoonotic",[72,27,71],{"code":94,"score":52,"supported":43,"title":95,"abstract":96,"tags":99},"I3",[],[97,98],"遥感","remote sensing",[],{"code":79,"score":101,"supported":43,"title":102,"abstract":103,"tags":105},3,[],[104],"livestock",[],[107,108],"裂谷热病毒 蜱传 汉坦病毒","One Health 人兽共患病 监测","裂谷热病毒蜱传汉坦病毒-4508","10.3390\u002Fv18101110",{"doi":110,"openalex_id":112,"authors":113,"venue":60,"cited_by_count":49,"oa_url":57,"card":120,"direction":126,"ingested_from":127},"W7221029769",[114,117],{"name":115,"orcid":116},"Daniel J.-M. Desmecht","https:\u002F\u002Forcid.org\u002F0000-0001-9440-0993",{"name":118,"orcid":119},"Hani Boshra","https:\u002F\u002Forcid.org\u002F0000-0001-9924-8126",{"tldr":121,"method":122,"finding":123,"direction":124,"opportunity":125},"从One Health视角综述裂谷热、克里米亚-刚果出血热和汉坦病毒的生态流行与防控。","文献综述，整合分子诊断、基因组流行病学、生态建模、遥感和气候预测。","气候变化、农业扩张和土地利用改变驱动这些人兽共患病溢出，需跨部门联合监测。","农业绿色发展与碳","可探索农业扩张与气候变化耦合下虫媒病毒溢出风险的遥感预警模型。","农业遥感与作物表型","openalex","2026-10-09T23:30:26.152648Z",{"id":130,"title":131,"url":132,"summary":133,"summary_zh":134,"content":8,"source_name":135,"source_url":132,"published_at":136,"category":62,"cover_url":8,"hotness":13,"is_selected":14,"score":137,"score_detail":138,"sources":142,"tags":144,"primary_topic":8,"secondary_topics":147,"classification":148,"search_phrases":161,"slug":164,"view_count":20,"doi":165,"paper":166,"created_at":190},4444,"Geostatistical modelling of the effect of vegetation on canine visceral leishmaniasis in Camaçari, Bahia State, Northeastern Brazil using remote-sensed data","https:\u002F\u002Fdoi.org\u002F10.1038\u002Fs41598-026-73205-3","Abstract Visceral leishmaniasis (VL) is a vector-borne disease that can cause fever, hepatosplenomegaly, weight loss and pancytopenia. In Brazil, VL occurs when a female phlebotomine sand fly ( Lutzomyia longipalpis ) takes a blood meal from an infected reservoir. Domestic canines are likely the main source of the infectious agent since they live in close proximity to humans and can remain asymptomatic for several years. Consequently, sole treatment of human cases likely cannot prevent transmission. Current methods of control have been unsuccessful, and thus, a better understanding of canine transmission and the effect of the environment is required. Phlebotomine sand flies feed on plant sap and nectar, and lay eggs around tree roots, hence, we hypothesise that dogs are more likely to contract VL near vegetation. In this retrospective study, we investigate the effect of vegetation on canine visceral leishmaniasis (CVL) in the community of Camaçari, Bahia, Northeastern Brazil using geostatistical modelling. The normalised vegetation index (NDVI) is used to quantify vegetation. We find that, on average, an increase in NDVI of 0.1 led to a 1.21-fold increase in the odds of CVL. The odds of CVL were highest along the coast where plant species known to attract Lutzomyia longipalpis have been identified.","摘要 内脏利什曼病（VL）是一种媒介传播疾病，可引起发热、肝脾肿大、体重减轻和全血细胞减少。在巴西，当雌性白蛉（长须罗蛉）从受感染的储存宿主吸血时，便会传播VL。家犬很可能是传染源的主要来源，因为它们与人类居住地距离很近，并且可以多年保持无症状。因此，仅治疗人类病例可能无法阻止传播。目前的控制方法并不成功，因此需要更好地了解犬类传播以及环境的影响。白蛉以植物汁液和花蜜为食，并在树根周围产卵，因此我们假设犬类在植被附近更容易感染VL。在这项回顾性研究中，我们使用地统计模型研究了植被对巴西东北部巴伊亚州卡马萨里社区犬内脏利什曼病（CVL）的影响。采用归一化植被指数（NDVI）量化植被。我们发现，平均而言，NDVI每增加0.1，CVL的比值比增加1.21倍。CVL的比值比在沿海地区最高，那里已鉴定出已知会吸引长须罗蛉的植物物种。","Scientific Reports","2026-10-06T00:00:00Z",68,{"impact":66,"substance":139,"depth":140,"authority":19,"freshness":66,"relevant":20,"comment":141},21,17,"基于遥感NDVI的地理统计建模揭示植被与犬内脏利什曼病传播关联，方法新颖、结论具体，对动物疫病遥感监测有参考价值，但属区域流行病学研究，与农业信息化关联偏弱。",[143],{"name":135,"url":132},[71,97,145,27,146],"NDVI","公共卫生",[],{"status":149,"locked":14,"version":33,"method":34,"evidence":150},"needs_review",{"candidates":151,"agricultural_evidence":14,"reason":160},[152,156],{"code":38,"score":39,"supported":14,"title":153,"abstract":154,"tags":155},[],[],[27,71],{"code":94,"score":39,"supported":14,"title":157,"abstract":158,"tags":159},[],[],[145,97],"农业相关性需要复核",[162,163],"Camaçari 犬内脏利什曼病 NDVI","巴西 植被 犬利什曼病 遥感","Camaçari犬内脏利什曼病NDVI-4444","10.1038\u002Fs41598-026-73205-3",{"doi":165,"openalex_id":167,"authors":168,"venue":135,"cited_by_count":49,"oa_url":184,"card":185,"direction":126,"ingested_from":127},"W7220723172",[169,172,175,178,181],{"name":170,"orcid":171},"F. Clark","https:\u002F\u002Forcid.org\u002F0000-0003-1083-0887",{"name":173,"orcid":174},"Manuela da Silva Solcà","https:\u002F\u002Forcid.org\u002F0000-0001-9014-8903",{"name":176,"orcid":177},"Deborah Bittencourt Mothé Fraga","https:\u002F\u002Forcid.org\u002F0000-0003-4788-0319",{"name":179,"orcid":180},"Cláudia Brodskyn","https:\u002F\u002Forcid.org\u002F0000-0003-3367-5365",{"name":182,"orcid":183},"Emanuele Giorgi","https:\u002F\u002Forcid.org\u002F0000-0003-0640-181X","https:\u002F\u002Fwww.nature.com\u002Farticles\u002Fs41598-026-73205-3_reference.pdf",{"tldr":186,"method":187,"finding":188,"direction":126,"opportunity":189},"用遥感NDVI和地统计模型分析巴西犬内脏利什曼病与植被的关系。","地统计建模，结合遥感NDVI数据与犬利什曼病病例。","NDVI每增加0.1，犬内脏利什曼病风险增加1.21倍，沿海植被区风险最高。","可拓展遥感植被指数至其他虫媒病或人畜共患病风险制图，结合多时相数据优化预警。","2026-10-08T23:30:32.248339Z",{"id":192,"title":193,"url":194,"summary":195,"summary_zh":8,"content":196,"source_name":197,"source_url":8,"published_at":198,"category":199,"cover_url":8,"hotness":200,"is_selected":43,"score":201,"score_detail":202,"sources":207,"tags":212,"primary_topic":217,"secondary_topics":218,"classification":219,"search_phrases":227,"slug":230,"view_count":101,"doi":8,"paper":8,"created_at":231},4116,"农业农村部公告第1069号：批准11种新兽药+3种兽药注册+3种兽药变更注册","https:\u002F\u002Fwww.agri.cn\u002Fzx\u002Fhxgg\u002F202609\u002Ft20260929_8874176.htm","农业农村部公告第1069号发布：根据《兽药管理条例》和《兽药注册办法》，批准枸橼酸马罗匹坦等11种兽药产品为新兽药（含枸橼酸马罗匹坦、枸橼酸马罗匹坦注射液、氟雷拉纳、氟雷拉纳滴剂、氟雷拉纳溶液、犬细小病毒免疫球蛋白、鸭病毒性肝炎二价活疫苗（1型BJ80株+3型HB80株）、鸡新城疫-禽流感（H9亚型）-传染性法氏囊病-禽腺病毒病（I群4型）四联灭活疫苗、麻杏石甘丸等），核发《新兽药注册证书》并发布产品质量标准、工艺规程、说明书和标签，自发布之日起执行；同时批准猫疱疹病毒1型胶体金检测试纸条等3种兽药产品注册，批准氟雷拉纳滴剂等3种兽药产品变更注册。","根据《兽药管理条例》和《兽药注册办法》规定，经审查，批准枸橼酸马罗匹坦 等 11 种兽药产品 为新兽药，核发《新兽药注册证书》，发布产品质量标准、工艺规程、说明书和标签，自发布之日起执行。\n\n批准猫疱疹病毒 1 型胶体金检测试纸条 等 3 种兽药产品 注册，发布产品质量标准、工艺规程、说明书和标签，自发布之日起执行。\n\n批准 氟雷拉纳滴剂 等 3 种兽药产品 变更注册，有关单位按照农业农村部批准的变更事项，自行修改原批准的说明书和标签对应内容，并印制、使用。\n\n特此公告。\n\n附件：1.新兽药注册目录\n\n2.兽药变更注册目录\n\n3.质量标准\n\n4.工艺规程\n\n5.说明书和标签\n\n农业农村部\n\n202 6 年 9 月 28 日\n\n附件 1\n\n新兽药注册目录\n\n新兽药名称 研制单位 类别 新兽药\n\n注册\n\n证书号 监测期 备注\n枸橼酸马罗匹坦 陕西汉江药业集团股份有限公司、珠海联邦动保有限公司、广东韶关欧芬生物医药科技开发有限公司、北京广博德赛医药技术开发有限责任公司、陕西省农业检验检测中心 二类（202 6）\n\n新兽药\n\n证字 114 号 4 年\u002F\n枸橼酸马罗匹坦\n\n注射液 湖南尚成生物科技有限公司、齐鲁动物保健品有限公司、内蒙古联邦动保药品有限公司、北京广博德赛医药技术开发有限责任公司、北京卫宠医药科技有限公司 二类（202 6）\n\n新兽药\n\n证字 115 号 4 年\u002F\n氟雷拉纳 华南农业大学、天津市中升挑战生物科技有限公司、浙江国邦药业有限公司、广东康羽生物科技研究院有限公司 二类（202 6）\n\n新兽药\n\n证字 116 号 4 年\u002F\n氟雷拉纳滴剂 华南农业大学、天津市中升挑战生物科技有限公司、青岛欧博方医药科技有限公司、四川康泉生物科技有限公司、广东康羽生物科技研究院有限公司 二类（202 6）\n\n新兽药\n\n证字 117 号 4 年\u002F\n氟雷拉纳溶液 天津市中升挑战生物科技有限公司、华南农业大学、吉林大学、保定冀中药业有限公司、河北远征药业有限公司、广东康羽生物科技研究院有限公司、山东牧邦动物药业有限公司 二类（202 6）\n\n新兽药\n\n证字 118 号 4 年\u002F\n犬细小病毒免疫\n\n球蛋白 泰州博莱得利生物科技有限公司、哈尔滨元亨生物药业有限公司 三类（202 6）\n\n新兽药\n\n证字 119 号 3 年\u002F\n鸭病毒性肝炎二价活疫苗（1 型 BJ80 株+3 型 HB80 株）国药集团动物保健股份有限公司、上海创宏生物科技有限公司、国药集团扬州威克生物工程有限公司、龙阔（苏州）生物工程有限公司、诗华动保科技（杭州）有限公司、瑞普生物股份有限公司 三类（202 6）\n\n新兽药\n\n证字 120 号 3 年\u002F\n鸡新城疫、禽流感（H9 亚型）、传染性法氏囊病、禽腺病毒病（I 群，4 型）四联灭活疫苗（La Sota 株+A15 株+VP2 蛋白+Fiber2 蛋白）北京华夏兴洋生物科技有限公司 三类（202 6）\n\n新兽药\n\n证字 121 号 3 年\u002F\n麻杏石甘丸 河北锦坤动物药业有限公司、四川德成动物保健品有限公司、四川金正康生物技术有限公司、河北农业大学、山东谊源药业股份有限公司、中兽医（汤阴）生物科技有限公司、石家庄市汇丰动物保健品有限公司、河北牧安动物药业有限公司 四类（202 6）\n\n新兽药\n\n证字 122 号\u002F\u002F\n盐酸沃尼妙林溶液 广东温氏大华农生物科技有限公司动物保健品厂、齐鲁动物保健品有限公司、华南农业大学 四类（202 6）\n\n新兽药\n\n证字 123 号 3 年 纳入兽用处方药管理\n醋酸泼尼松龙片 北京生泰尔科技股份有限公司、爱迪森（北京）生物科技有限公司、生泰尔（内蒙古）科技有限公司、北京爱宠族科技有限公司、爱宠族（江苏）科技有限公司、五洲牧洋（黑龙江）科技有限公司、爱迪森（江苏）生物科技有限公司、北京华夏兴洋生物科技有限公司 四类（202 6）\n\n新兽药\n\n证字 124 号 3 年 纳入兽用处方药管理\n猫疱疹病毒 1 型胶体金检测试纸条 武汉科前生物股份有限公司、华中农业大学\u002F\u002F\u002F\u002F\n猪圆环病毒 2 型、3 型双重荧光 PCR 检测\n\n试剂盒 湖南冠牧生物科技有限公司、重庆海关技术中心\u002F\u002F\u002F\u002F\n猫泛白细胞减少症病毒胶体金检测试纸条 广州源博医药科技有限公司、源和动物保健（广东）有限公司\u002F\u002F\u002F\u002F\n\n附件 2\n\n兽药 变更 注册目录\n\n兽药名称 申请 单位 兽药标准来源 变更事项 监测期（针对变更事项）\n氟雷拉纳滴剂 齐鲁动物保健品有限公司（2026）\n\n新兽药\n\n证字 1 号 有效期由 24 个月变更为 36 个月\u002F\n氟雷拉纳莫昔克丁滴剂 齐鲁动物保健品有限公司（2026）\n\n新兽药\n\n证字 40 号 有效期由 24 个月变更为 36 个月\u002F\n盐酸聚六亚甲基双胍溶液 天津市中升挑战生物科技有限公司（2025）\n\n新兽药\n\n证字 120 号 有效期由 24 个月变更为 36 个月\u002F\n\n附件下载：\n\n[说明书和标签.pdf](https:\u002F\u002Fwww.agri.cn\u002Fzxfile\u002Freader?file=https:\u002F\u002Fwww.agri.cn\u002Fzx\u002Fhxgg\u002F202609\u002FP020260929335614913184.pdf)","中国农业农村信息网·2026年9月29日","2026-09-29T00:00:00Z","政策",25,89,{"impact":203,"substance":204,"depth":17,"authority":205,"freshness":52,"relevant":20,"comment":206},26,24,15,"农业农村部全国性兽药注册公告，含11种新兽药、3种注册及3种变更注册的完整目录与监测期细节，政策信息增量高，但发布已逾一周，时效性一般。",[208,209],{"name":197,"url":194},{"name":210,"url":211},"新疆生产建设兵团农业农村局 2026-09-30","http:\u002F\u002Fnyj.xjbt.gov.cn\u002Fc\u002F2026-09-30\u002F8506894.shtml",[25,213,214,215,216],"兽药注册","新兽药","宠物用药","兽用处方药",{"code":38,"slug":76,"name":77,"path":78,"parent_code":79},[],{"status":82,"locked":14,"version":33,"method":34,"evidence":220},{"candidates":221,"agricultural_evidence":43},[222],{"code":38,"score":19,"supported":43,"title":223,"abstract":225,"tags":226},[224],"兽药",[224],[213,25,214],[228,229],"农业农村部 第1069号 新兽药","氟雷拉纳滴剂 变更注册","农业农村部第1069号新兽药-4116","2026-10-04T00:09:04.480727Z",{"id":233,"title":234,"url":235,"summary":236,"summary_zh":237,"content":8,"source_name":238,"source_url":235,"published_at":239,"category":62,"cover_url":8,"hotness":13,"is_selected":14,"score":240,"score_detail":241,"sources":243,"tags":245,"primary_topic":249,"secondary_topics":250,"classification":262,"search_phrases":301,"slug":304,"view_count":39,"doi":305,"paper":306,"created_at":321},3617,"Applications and challenges of geospatial technologies in veterinary medicine","https:\u002F\u002Fdoi.org\u002F10.1007\u002Fs44338-026-00259-y","Geospatial technologies are increasingly recognized as critical assets in veterinary medicine, providing robust frameworks for disease surveillance, risk mapping, and informed decision‑making. The objective of this narrative review is to summarize the role of Geographic Information Systems, Global Positioning System, and Remote Sensing in advancing veterinary medicine by synthesizing current applications, identifying prevailing challenges, and exploring future prospects. Collectively, these tools enable monitoring of disease dynamics, identification of epidemiological hotspots, outbreak prediction, and integration of spatial and epidemiological datasets to guide targeted interventions. For instance, GIS‑based mapping of Rift Valley fever outbreaks in East Africa has enabled rapid identification of epidemiological hotspots and guided vaccination campaigns, while RS‑derived vegetation indices have successfully predicted tick distribution patterns in southern Africa, improving targeted control strategies. Their utility extends beyond livestock health, contributing significantly to wildlife disease monitoring, zoonotic risk assessment, food safety assurance, and broader veterinary decision processes. Despite such successes, adoption remains limited, hindered by technical\u002Finfrastructure barriers, poor data quality, and ethical and policy challenges. In Ethiopia, recent surveys indicate that fewer than 20% of veterinary institutions actively use GIS platforms for routine surveillance, and integration of RS into national veterinary services is still limited to pilot projects. This gap underscores the urgent need for national geospatial data repositories, standardized protocols, and capacity‑building initiatives to ensure equitable access and sustainable utilization. Future opportunities lie in harnessing advances in Artificial Intelligence, Machine Learning, and cloud‑based GIS platforms, alongside global collaboration and training programs, to strengthen veterinary epidemiology and surveillance systems. Addressing these challenges will be essential for the sustainable integration of geospatial technologies into veterinary practice, thereby enhancing disease control, safeguarding public health, and supporting livestock productivity.","地理空间技术在兽医学中日益被视为关键资产，为疾病监测、风险制图和知情决策提供了稳健框架。本叙述性综述旨在总结地理信息系统（Geographic Information Systems, GIS）、全球定位系统（Global Positioning System, GPS）和遥感（Remote Sensing, RS）在推动兽医学发展中的作用，通过综合当前应用、识别主要挑战并探讨未来前景。总体而言，这些工具有助于监测疾病动态、识别流行病学热点、预测疫情，并整合空间与流行病学数据集以指导针对性干预。例如，基于GIS的东非裂谷热疫情制图能够快速识别流行病学热点并指导疫苗接种活动，而遥感衍生的植被指数已成功预测南部非洲蜱虫分布模式，改善了针对性控制策略。其效用不仅限于家畜健康，还对野生动物疾病监测、人兽共患病风险评估、食品安全保障及更广泛的兽医决策过程作出重要贡献。尽管取得了这些成功，其应用仍然有限，受到技术\u002F基础设施障碍、数据质量不佳以及伦理和政策挑战的制约。在埃塞俄比亚，近期调查表明，不到20%的兽医机构在常规监测中积极使用GIS平台，而遥感纳入国家兽医服务仍局限于试点项目。这一差距凸显了建立国家地理空间数据存储库、标准化方案和能力建设举措的迫切需求，以确保公平获取和可持续利用。未来的机遇在于利用人工智能、机器学习和基于云的GIS平台的进步，以及全球合作和培训项目，来加强兽医流行病学和监测系统。应对这些挑战对于将地理空间技术可持续地整合到兽医实践中至关重要，从而增强疾病控制、保障公共卫生并支持家畜生产力。","Discover Animals","2026-09-24T00:00:00Z",75,{"impact":17,"substance":65,"depth":140,"authority":86,"freshness":66,"relevant":20,"comment":242},"综述系统梳理GIS、GPS与遥感在兽医领域的应用与瓶颈，含东非裂谷热、南部非洲蜱虫分布及埃塞俄比亚使用率不足20%等实证数据，对农业信息化与动物疫病防控有参考价值。",[244],{"name":238,"url":235},[71,246,27,247,248],"遥感监测","兽医信息化","地理信息系统",{"code":38,"slug":76,"name":77,"path":78,"parent_code":79},[251,257],{"code":252,"slug":253,"name":254,"path":255,"parent_code":256},"I4","gis","GIS与空间分析","\u002Ftopic\u002Fdigital-agriculture\u002Fgis","I",{"code":258,"slug":259,"name":260,"path":261,"parent_code":256},"I2","agricultural-ai","农业AI与大模型","\u002Ftopic\u002Fdigital-agriculture\u002Fagricultural-ai",{"status":82,"locked":14,"version":33,"method":34,"evidence":263},{"candidates":264,"agricultural_evidence":43},[265,270,277,285,290,297],{"code":38,"score":266,"supported":43,"title":267,"abstract":268,"tags":269},19,[90],[89,90,91],[27,71],{"code":252,"score":13,"supported":43,"title":271,"abstract":272,"tags":276},[],[273,274,275],"地理信息","GIS","geographic information",[248],{"code":258,"score":278,"supported":43,"title":279,"abstract":280,"tags":284},9,[],[281,282,283],"机器学习","machine learning","artificial intelligence",[],{"code":94,"score":286,"supported":43,"title":287,"abstract":288,"tags":289},7,[],[97,98],[246],{"code":291,"score":52,"supported":43,"title":292,"abstract":293,"tags":296},"E4",[],[294,295],"食品安全","food safety",[],{"code":79,"score":101,"supported":43,"title":298,"abstract":299,"tags":300},[],[104],[],[302,303],"GIS 兽医 疾病监测","遥感 蜱虫 分布 预测","GIS兽医疾病监测-3617","10.1007\u002Fs44338-026-00259-y",{"doi":305,"openalex_id":307,"authors":308,"venue":238,"cited_by_count":49,"oa_url":314,"card":315,"direction":320,"ingested_from":127},"W7214225608",[309,312],{"name":310,"orcid":311},"Assaye Wollelie Fentie","https:\u002F\u002Forcid.org\u002F0009-0005-9099-9819",{"name":313,"orcid":8},"Daniel Haile Asefa","https:\u002F\u002Flink.springer.com\u002Fcontent\u002Fpdf\u002F10.1007\u002Fs44338-026-00259-y.pdf",{"tldr":316,"method":317,"finding":318,"direction":126,"opportunity":319},"综述地理空间技术在兽医领域的应用、挑战与前景，聚焦疾病监测与风险制图。","叙述性综述，整合GIS、GPS、遥感在兽医流行病学中的应用案例与调查数据。","GIS\u002FRS能有效预测疫情和病媒分布，但应用受限于基础设施、数据质量及政策，如埃塞俄比亚使用率不足2","可探索AI\u002F机器学习与云GIS结合，构建兽医领域标准化地理空间数据平台与预警系统。","智慧农业 \u002F 农业物联网","2026-09-27T23:30:26.015992Z",{"id":323,"title":324,"url":325,"summary":326,"summary_zh":8,"content":327,"source_name":328,"source_url":8,"published_at":329,"category":199,"cover_url":8,"hotness":13,"is_selected":43,"score":330,"score_detail":331,"sources":334,"tags":336,"primary_topic":340,"secondary_topics":341,"classification":342,"search_phrases":360,"slug":363,"view_count":286,"doi":8,"paper":8,"created_at":364},2442,"农业农村部公告第 1062 号:批准氟雷拉纳等 17 种新兽药+6 种注册+2 种变更","https:\u002F\u002Fwww.agri.cn\u002Fzx\u002Fhxgg\u002F202609\u002Ft20260914_8870844.htm","农业农村部 9 月 11 日发布第 1062 号公告,批准氟雷拉纳(山东诚汇双达)、氟雷拉纳咀嚼片(湖南尚成生物)、盐酸地那维林、盐酸地那维林注射液、多西环素一水合物、多西环素内服糊剂等 17 种兽药产品为新兽药,核发《新兽药注册证书》;批准犬、猫狂犬病病毒抗体胶体金检测试纸条等 6 种兽药产品注册;批准伊维菌素等 2 种兽药产品变更注册。同步发布产品质量标准、工艺规程、说明书、标签、日允许摄入量和最大残留限量标准(试行),自发布之日起执行,覆盖宠物用药、畜禽疫苗、水产养殖、检测诊断试剂等方向。","根据《兽药管理条例》和《兽药注册办法》规定，经审查，批准氟雷拉纳 等 17 种兽药产品 为新兽药，核发《新兽药注册证书》，发布产品质量标准、工艺规程、说明书、标签、日允许摄入量和最大残留限量标准（试行），自发布之日起执行。\n\n批准犬、猫狂犬病病毒抗体胶体金检测试纸条 等 6 种兽药产品 注册，发布产品质量标准、工艺规程、说明书和标签，自发布之日起执行。\n\n批准伊维菌素 等 2 种兽药产品 变更注册，有关单位按照农业农村部批准的变更事项，自行修改原批准的说明书和标签对应内容，并印制、使用。\n\n特此公告。\n\n附件：1.新兽药注册目录\n\n2.兽药变更注册目录\n\n3.质量标准\n\n4.工艺规程\n\n5.说明书和标签\n\n6.日允许摄入量和最大残留限量标准（试行）\n\n农业农村部\n\n202 6 年 9 月 11 日\n\n附件 1\n\n新兽药注册目录\n\n新兽药名称 研制单位 类别 新兽药\n\n注册\n\n证书号 监测期 备注\n氟雷拉纳 山东诚汇双达药业有限公司 二类（202 6）\n\n新兽药\n\n证字 97 号 4 年\u002F\n氟雷拉纳咀嚼片 湖南尚成生物科技有限公司、邵阳鑫牧生物科技有限公司、长沙东典药业有限公司、湖南省兽药饲料监察所 二类（202 6）\n\n新兽药\n\n证字 98 号 4 年\u002F\n盐酸地那维林 厦门欧瑞捷生物科技有限公司、天津市中升挑战生物科技有限公司、广西大学 二类（202 6）\n\n新兽药\n\n证字 99 号 4 年\u002F\n盐酸地那维林注射液 天津市中升挑战生物科技有限公司、厦门欧瑞捷生物科技有限公司、洛阳惠中兽药有限公司、西北农林科技大学 二类（202 6）\n\n新兽药\n\n证字 100 号 4 年\u002F\n多西环素一水合物 丽珠集团福州福兴医药有限公司 二类（202 6）\n\n新兽药\n\n证字 101 号 4 年 纳入兽用处方药管理\n多西环素内服糊剂 毛孩子动物保健（广东）有限公司 二类（202 6）\n\n新兽药\n\n证字 102 号 4 年 纳入兽用处方药管理\n倍苏溶液 北京生泰尔科技股份有限公司、生泰尔（内蒙古）科技有限公司、浙江省淡水水产研究所（浙江省淡水渔业环境监测站）、爱迪森（江苏）生物科技有限公司、五洲牧洋（黑龙江）科技有限公司、北京爱宠族科技有限公司、爱宠族（江苏）科技有限公司、北京华夏兴洋生物科技有限公司、爱迪森（北京）生物科技有限公司 三 类（202 6）\n\n新兽药\n\n证字 103 号 3 年\u002F\n连桑荆菊口服液 西北农林科技大学、山东百晟药业有限公司、清远海贝生物技术有限公司、山东德青制药有限责任公司、石家庄市九洲兽药有限公司、四川德成动物保健品有限公司、江西中成药业集团有限公司、西安雨田农业科技股份有限公司 三 类（202 6）\n\n新兽药\n\n证字 104 号 3 年\u002F\n荆防可溶性粉 保定冀中药业有限公司、中国农业大学、保定阳光本草药业有限公司、甘肃农业大学 三类（202 6）\n\n新兽药\n\n证字 105 号 3 年\u002F\n九味清瘟颗粒 山西农业大学、淄博维希尔生物技术有限公司、河北地邦动物保健科技有限公司、江西嘉博生物工程有限公司、济南广盛源生物科技有限公司、江西邦诚动物药业有限公司、陕西本草医药控股集团有限公司、四川欧邦生物科技有限公司 三类（202 6）\n\n新兽药\n\n证字 106 号 3 年\u002F\n禽流感（H9 亚型）灭活疫苗（HF 株）诗华动保科技（北京）有限公司、诗华动保科技（杭州）有限公司 三类（202 6）\n\n新兽药\n\n证字 107 号 3 年\u002F\n猫鼻气管炎、杯状病毒病、泛白细胞减少症三联灭活疫苗（WH-2017 株+LZ-2016 株+CS-2016 株）华中农业大学、武汉科前生物股份有限公司、云南生物制药有限公司、华派生物技术（集团）股份有限公司 三类（202 6）\n\n新兽药\n\n证字 108 号 3 年\u002F\n猪链球菌、副猪格拉瑟菌、猪圆环病毒 2 型三联灭活疫苗（2 型 QH 株+5 型 LZ 株+Cap 蛋白）山东省农业科学院畜牧兽医研究所、山东省农业科学院家禽研究所、山东滨州沃华生物工程有限公司、青岛蔚蓝动物保健集团有限公司、石家庄圣澳生物科技有限公司 三类（202 6）\n\n新兽药\n\n证字 109 号 3 年\u002F\n禽流感（H9 亚型）灭活疫苗（细胞源，CN 株）肇庆大华农生物药品有限公司、华南农业大学、华农（肇庆）生物产业技术研究院有限公司、华东理工大学 三类（202 6）\n\n新兽药\n\n证字 110 号 3 年\u002F\n猪圆环病毒 2 型重组杆状病毒灭活疫苗\n\n（TZ 株）华威特（江苏）生物制药有限公司 三类（202 6）\n\n新兽药\n\n证字 111 号 3 年\u002F\n清营颗粒 山东省农业科学院家禽研究所、济南森康三峰生物工程有限公司、山东鑫谷健康产业有限公司、山东德青制药有限责任公司、山东德州神牛药业有限公司、青岛蔚蓝生物股份有限公司、中国农业大学、山东省农业科学院畜牧兽医研究所、浙江大学 四 类（202 6）\n\n新兽药\n\n证字 112 号 3 年\u002F\n注射用尖吻蝮蛇血凝酶 北京康辰药业股份有限公司、北京爱欣湾医药科技有限公司 四类（202 6）\n\n新兽药\n\n证字 113 号 3 年 纳入兽用处方药管理\n犬、猫狂犬病病毒抗体胶体金检测试纸条 长春西诺生物科技有限公司\u002F\u002F\u002F\u002F\n十足目虹彩病毒 1 荧光 PCR 检测试剂盒 中国水产科学研究院黄海水产研究所、青岛立见生物科技有限公司\u002F\u002F\u002F\u002F\n犬腺病毒 Ⅰ 型荧光 PCR 检测试剂盒 北京纳百生物科技有限公司\u002F\u002F\u002F\u002F\n布鲁氏菌核酸恒温荧光扩增检测试剂盒 禾旭（郑州）生物技术有限公司、中国农业科学院北京畜牧兽医研究所、山东省动物疫病预防与控制中心（山东省人畜共患病流调监测中心）、中国农业大学、青海大学\u002F\u002F\u002F\u002F\n猫泛白细胞减少症病毒胶体金检测试纸条 中牧实业股份有限公司\u002F\u002F\u002F\u002F\n牛副结核分枝杆菌间接 ELISA 抗体检测试剂盒 中国农业科学院哈尔滨兽医研究所、深圳市爱医生物科技有限公司\u002F\u002F\u002F\u002F\n\n附件 2\n\n兽药 变更 注册目录\n\n兽药名称 申请 单位 兽药标准来源 变更事项 监测期（针对变更事项）\n伊维菌素 山东齐发药业有限公司《中国兽药典》2020 年版一部同品种相应内容 有效期由“36 个月”变更为“48 个月”\u002F\n猪口蹄疫 O 型、A 型二价合成肽疫苗（多肽 2700+2800+MM13）申联生物医药（上海）股份有限公司、中国农业科学院兰州兽医研究所、中农威特生物科技股份有限公司（2018）\n\n新兽药\n\n证字 71 号 质量标准、工艺规程、说明书和内包装标签中【作用与用途】及相关内容由“用于预防猪 O 型、A 型口蹄疫。免疫期为 6 个月”变更为“用于预防猪口蹄疫 O 型缅甸 98（Mya-98）谱系和 A 型东南亚 97（SEA-97）谱系。免疫产生期为 28 日，免疫期为 6 个月”\u002F\n\n附件下载：\n\n[说明书和标签、日允许摄入量和最大残留限量标准（试行）.pdf](https:\u002F\u002Fwww.agri.cn\u002Fzxfile\u002Freader?file=https:\u002F\u002Fwww.agri.cn\u002Fzx\u002Fhxgg\u002F202609\u002FP020260914335618129795.pdf)","中国农业农村信息网 2026-09-14","2026-09-10T16:00:00Z",90,{"impact":203,"substance":332,"depth":17,"authority":205,"freshness":66,"relevant":20,"comment":333},23,"农业农村部全国性兽药审批公告，含17种新兽药、6种注册及2种变更的完整目录与监测期细节，政策条款与数据增量充分，权威性和时效性俱佳，值得进入每日精选。",[335],{"name":328,"url":325},[25,337,215,338,339],"兽药审批","新兽药注册","畜产品质量安全",{"code":38,"slug":76,"name":77,"path":78,"parent_code":79},[],{"status":82,"locked":14,"version":33,"method":34,"evidence":343},{"candidates":344,"agricultural_evidence":43},[345,349,354],{"code":38,"score":86,"supported":43,"title":346,"abstract":347,"tags":348},[224],[224],[25],{"code":79,"score":101,"supported":43,"title":350,"abstract":351,"tags":353},[],[352],"畜禽",[],{"code":355,"score":101,"supported":43,"title":356,"abstract":357,"tags":359},"D",[],[358],"水产",[],[361,362],"畜产品质量安全 新兽药注册 兽药审批 动物疫苗","畜产品质量安全 新兽药注册","畜产品质量安全新兽药注册兽药审批动物疫苗-2442","2026-09-15T00:04:19.704183Z",{"id":366,"title":367,"url":368,"summary":369,"summary_zh":370,"content":8,"source_name":371,"source_url":368,"published_at":372,"category":62,"cover_url":8,"hotness":13,"is_selected":14,"score":49,"score_detail":373,"sources":375,"tags":377,"primary_topic":379,"secondary_topics":380,"classification":381,"search_phrases":396,"slug":399,"view_count":39,"doi":400,"paper":401,"created_at":412},2438,"The Ecology, Identification and Control of Bunyaviruses from a One Health Perspective","https:\u002F\u002Fdoi.org\u002F10.20944\u002Fpreprints202609.0941.v1","Zoonotic viral diseases continue to pose major challenges to global health, particularly as environmental, social and economic changes increasingly influence interactions among humans, animals, vectors, and ecosystems. This review explores Rift Valley fever virus (RVFV), Crimean-Congo hemorrhagic fever virus (CCHFV), and hantaviruses (HTVs) within the framework of One Health, emphasizing the ecological and epidemiological factors that govern their emergence and transmission. Despite their distinct transmission cycles, these viruses share important determinants of zoonotic risk. RVFV is primarily maintained through interactions among mosquitoes, livestock, wildlife, and humans; CCHFV is sustained within complex tick–vertebrate systems involving Hyalomma ticks, domestic animals, and wildlife; while HTVs are predominantly maintained through persistent infections in mammalian reservoir hosts, particularly rodents. Climate variability, habitat alteration, agricultural expansion, livestock movement, urbanization, and other anthropogenic pressures can modify these transmission systems and create new opportunities for pathogen spillover. Effective prevention and control therefore require integrated surveillance that encompasses human disease, animal populations, vectors or wildlife reservoirs, and environmental conditions. Advances in molecular diagnostics, genomic epidemiology, ecological modeling, remote sensing, and climate-based forecasting provide valuable opportunities for improving early detection and outbreak preparedness. Ultimately, the experiences of RVFV, CCHFV, and HTVs that reducing the burden of zoonotic viral diseases requires sustained collaboration among human and veterinary health professionals, ecologists, entomologists, environmental scientists, and public health authorities. A coordinated One Health approach is consequently essential for anticipating emerging threats, strengthening preparedness, and protecting human, animal, and ecosystem health.","人兽共患病毒病持续对全球健康构成重大挑战，尤其是当环境、社会和经济变化日益影响人类、动物、媒介和生态系统之间的相互作用时。本综述在“同一健康”（One Health）框架下探讨了裂谷热病毒（RVFV）、克里米亚-刚果出血热病毒（CCHFV）和汉坦病毒（HTVs），重点关注决定其出现和传播的生态学与流行病学因素。尽管这些病毒的传播循环各不相同，但它们共享重要的人兽共患风险决定因素。RVFV主要通过蚊虫、家畜、野生动物和人类之间的相互作用维持传播；CCHFV在涉及璃眼蜱属蜱虫、家畜和野生动物的复杂蜱-脊椎动物系统中持续循环；而HTVs主要通过哺乳动物储存宿主（尤其是啮齿动物）的持续性感染维持。气候变异性、栖息地改变、农业扩张、家畜流动、城市化及其他人为压力可改变这些传播系统，并为病原体外溢创造新的机会。因此，有效的预防和控制需要涵盖人类疾病、动物种群、媒介或野生动物储存宿主以及环境条件的综合监测。分子诊断、基因组流行病学、生态建模、遥感和基于气候的预测方面的进展为改善早期发现和疫情准备提供了宝贵机遇。最终，RVFV、CCHFV和HTVs的经验表明，减轻人兽共患病毒病的负担需要人类与兽医卫生专业人员、生态学家、昆虫学家、环境科学家和公共卫生当局之间的持续合作。因此，协调的“同一健康”方法对于预判新发威胁、加强准备以及保护人类、动物和生态系统健康至关重要。","Preprints.org","2026-09-11T00:00:00Z",{"impact":49,"substance":49,"depth":49,"authority":49,"freshness":49,"relevant":49,"comment":374},"该文为公共卫生领域的人兽共患病毒综述，与三农、农业信息化、智慧农业等主题无直接关联，不建议进入每日精选。",[376],{"name":371,"url":368},[71,72,27,378],"虫媒传染病",{"code":38,"slug":76,"name":77,"path":78,"parent_code":79},[],{"status":82,"locked":14,"version":33,"method":34,"evidence":382},{"candidates":383,"agricultural_evidence":43},[384,388,392],{"code":38,"score":86,"supported":43,"title":385,"abstract":386,"tags":387},[],[89,90,91],[72,27,71],{"code":94,"score":52,"supported":43,"title":389,"abstract":390,"tags":391},[],[97,98],[],{"code":79,"score":101,"supported":43,"title":393,"abstract":394,"tags":395},[],[104],[],[397,398],"动物疫病防控 人兽共患病 虫媒传染病 One Health","动物疫病防控 人兽共患病","动物疫病防控人兽共患病虫媒传染病OneHealth-2438","10.20944\u002Fpreprints202609.0941.v1",{"doi":400,"openalex_id":402,"authors":403,"venue":371,"cited_by_count":49,"oa_url":368,"card":407,"direction":126,"ingested_from":127},"W7212458598",[404,406],{"name":405,"orcid":8},"Daniel Desmecht",{"name":118,"orcid":8},{"tldr":408,"method":409,"finding":410,"direction":124,"opportunity":411},"从One Health视角综述裂谷热、克里米亚-刚果出血热和汉坦病毒的生态、鉴定与防控。","文献综述，整合分子诊断、基因组流行病学、生态建模、遥感与气候预测。","三种人兽共患病毒溢出风险受气候、栖息地改变、农业扩张和牲畜流动等驱动，需跨部门联合监测。","可探索农业扩张与牲畜流动如何量化驱动病毒溢出，并构建遥感与气候耦合的早期预警模型。","2026-09-14T23:30:27.836713Z"]