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基因编辑湖羊新种质创制」项目合作签约仪式。院党委委员、副院长王冉与乾宝牧业董事长王跃程出席。乾宝牧业拥有国内单体规模最大的湖羊核心种群，其培育的乾宝湖羊作为国内唯一肉羊优秀母本入驻海南崖州湾国家实验室。双方将系统开展新种质性能评价，推动实验室成果走向养殖一线，联手打造肉羊生物育种创新样板。",null,"10月16日，我院畜牧研究所与江苏乾宝牧业有限公司举行“MSTN基因编辑湖羊新种质创制”项目合作签约仪式。院党委委员、副院长王冉，乾宝牧业董事长王跃程、总裁蒋柏林出席活动，畜牧所相关负责人，以及双方科研骨干和相关负责人参加签约活动。\n\n王冉表示，种业是农业的“芯片”，畜禽种质创新是种业振兴的重要抓手，基因编辑等生物育种技术是畜禽育种变革的重要方向。期待双方以本次签约为契机，聚焦产业与企业实际需求，聚力破解技术转化落地难题，系统开展新种质性能评价，推动实验室科研成果走向养殖一线，以院企协同创新助力江苏肉羊种业高质量发展。\n\n王跃程介绍，湖羊是我国肉羊养殖的当家母本，也是江苏享誉全国的国宝级地方畜禽种质资源，更是乾宝牧业的核心资产。乾宝牧业深耕湖羊育种十余年，先后获评国家肉羊核心育种场、国家种业阵型企业、农业产业化国家重点龙头企业等，已成为国内湖羊产业领军企业，拥有国内单体规模最大的湖羊核心种群，种质资源领先行业一至两个代次，其培育的乾宝湖羊作为国内唯一肉羊优秀母本入驻海南崖州湾国家实验室。本次联合开展MSTN基因编辑湖羊创制，有望突破传统育种技术瓶颈，加速培育具有自主知识产权的突破性湖羊新种质。\n\n签约现场，相关科研人员汇报了“MSTN基因编辑湖羊新种质创制”项目实施方案，详细阐述种质群体创建流程与技术路线，厘清了双方任务分工与关键时间节点。双方还围绕生物安全管理规范、主体责任落实、后续项目申报等事项开展深入交流，进一步统一实施思路，细化落地推进举措。\n\n本次签约，标志着院企双方在动物生物育种领域的产学研协同攻关正式启动。下一步，双方将严格按照合作方案稳步推进各项工作，充分发挥畜牧所技术研发优势与乾宝牧业产业落地优势，加快基因编辑湖羊新种质创制步伐，打造肉羊生物育种创新样板，共同携手为我国湖羊种业升级、肉羊产业高质量发展提供科技支撑。","江苏省农业科学院 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乾宝牧业 湖羊","MSTN 基因编辑 湖羊","江苏省农科院乾宝牧业湖羊-5428",0,"2026-10-21T00:10:00.642077Z",{"total":85,"page":22,"page_size":85,"items":86},6,[87,139,226,277,317,368],{"id":88,"title":89,"url":90,"summary":91,"summary_zh":8,"content":92,"source_name":93,"source_url":8,"published_at":94,"category":12,"cover_url":8,"hotness":13,"is_selected":52,"score":95,"score_detail":96,"sources":102,"tags":104,"primary_topic":108,"secondary_topics":109,"classification":111,"search_phrases":133,"slug":136,"view_count":137,"doi":8,"paper":8,"created_at":138},1088,"破解世界难题 我国奶牛育种实现重要突破:山东农科院畜牧所联合奥克斯培育国内首例基因编辑短毛耐热荷斯坦牛","https:\u002F\u002Fwww.stdaily.com\u002Fweb\u002Fgdxw\u002F2026-08\u002F27\u002Fcontent_570945.html","8月26日,记者在山东省农科院畜牧兽医研究所研究基地发现,该所与合作伙伴奥克斯畜牧种业培育出国内首例具有综合育种值的基因编辑短毛耐热荷斯坦牛,具有短毛抗热性状,减产有望控制在10%以内。该团队利用基因编辑技术对来自高育种值奶牛体细胞进行了定向改良,获得双等位基因编辑犊牛,仅用一个世代便实现耐热性状导入,将短毛耐热荷斯坦牛GTPI提升至2980,达到国际先进水平。","科技日报记者 王延斌 通讯员 陈建志\n\n炎热天气通过“热应激”抑制奶牛采食、代谢与健康，导致产奶量下降20%—30%，是奶业发展的世界难题。8月26日，记者从山东省农科院畜牧兽医研究所（以下简称“畜牧所”）获悉，该所与合作伙伴培育出国内首例具有综合育种值的基因编辑短毛耐热荷斯坦牛，具有短毛抗热性状，减产有望控制在10%以内，为解决上述难题提供了中国答案。\n\n“该研究突破了传统育种效率低、周期长的限制，建立了以关键功能基因为靶标的精准育种新路径，对于推动我国奶牛种业升级和新种质战略储备具有重要意义。”农业农村部畜禽生物组学重点实验室主任，畜牧所党委书记黄金明说。\n\n![Image 1](https:\u002F\u002Fwww.stdaily.com\u002Fweb\u002Fgdxw\u002Fpic\u002F2026-08\u002F27\u002F570945_f66a6b7f-9cd3-4e41-9c38-aad6ad7112a6copy.jpg)\n\n基因编辑团队科研人员正在做实验\n集多项优点于一身，中国顶尖奶牛诞生\n\n荷斯坦牛是原产于荷兰北部的世界产奶量最高、存栏最广的专用乳牛品种，俗称“黑白花奶牛”，全球约80%—90%的奶牛为其后代。\n\n记者眼前的这头荷斯坦牛母犊（即雌性小牛）大约一米高，体型健硕，黑白花色，与普通犊牛相比，该母犊的短毛特征明显。“这是我们追求的，也是基因编辑的结果。”在上述项目专家、畜牧所副研究员肖遥看来，该团队利用基因编辑技术对来自高育种值奶牛体细胞进行了定向改良，获得双等位基因编辑犊牛，仅用一个世代（荷斯坦牛的世代间隔一般为5年左右）便实现耐热性状导入，将短毛耐热荷斯坦牛GTPI提升至2980。\n\n在中国荷斯坦牛育种体系中，奶牛综合育种值≥2800即属于前1%—2%的顶尖梯队。“2980”意味着其在产奶量、乳成分、体型及健康等性状上的遗传潜力处于国际先进水平，其后代预期将表现出显著高于平均水平的产奶性能与综合经济效益。畜牧所研究员高运东向记者表示：“我们生产的基因编辑奶牛的综合育种值为2980，达到了国际先进水平，同步实现了耐热性状的导入与遗传水平的提升。”\n\n![Image 2](https:\u002F\u002Fwww.stdaily.com\u002Fweb\u002Fgdxw\u002Fpic\u002F2026-08\u002F27\u002F570945_0d1028d3-27b2-4297-81e4-8ee3dbebdedccopy.jpg)\n\n这是5月龄的国内首例具有综合育种值的基因编辑短毛耐热荷斯坦牛\n“除了破解热应激导致减产瓶颈，我们还破解了多项关键难题。”黄金明表示，我们解决了育种周期长与性状冲突的问题，即突破了传统选育需多代回交才能导入单一性状的局限，仅用一代即完成耐热性状导入且不降低原有高产育种值，大幅缩短育种周期。此外，该团队克服了大动物基因编辑易出现嵌合体、编辑效率低及遗传不稳定的技术障碍，实现了目标基因纯合修饰与稳定遗传。\n\n在黄金明看来，上述“国内首例”的出现，也是“科学家+企业家”携手破局的结果。\n\n![Image 3](https:\u002F\u002Fwww.stdaily.com\u002Fweb\u002Fgdxw\u002Fpic\u002F2026-08\u002F27\u002F570945_a1f0fdd3-f308-4acf-82ac-3f42a1bffa73copy.jpg)\n\n基因编辑小组成员杨春红正在将大量待筛选的基因编辑细胞放入培养箱中\n科学家搭档企业家破解难题\n\n高运东拥有双重身份，一方面，他是畜牧所研究员，是上述项目的主要研发者之一，另一方面，他是山东奥克斯畜牧种业有限公司（以下简称“奥克斯”）董事长。\n\n该企业建有国家核心种公牛站、入选国家种业阵型补短板企业，牵头国家奶牛良种联合攻关项目，主持国家生物育种重大专项奶牛项目，是业界公认的奶牛育种行业的领军企业，从“国内首例”的出现提供着软、硬件支持。\n\n早在2004年，畜牧所便牵头联合奥克斯启动了山东首个奶牛分子育种与基因组选择技术攻关项目；到了2019年，奥克斯牵头，联合畜牧兽医所等单位承接国家奶牛良种联合攻关计划，这是国内唯一由企业牵头的奶牛种业国家级攻关项目。\n\n![Image 4](https:\u002F\u002Fwww.stdaily.com\u002Fweb\u002Fgdxw\u002Fpic\u002F2026-08\u002F27\u002F570945_4824c22d-1bf6-4ab6-a3e5-1e0b41776223copy.jpg)\n\n基因编辑团队科研人员正在做实验\n26年来，双方承担的项目聚焦基因组选择育种、基因编辑育种、体外胚胎生产等技术研发，特色种质创制和核心种质选育，良种产业化扩繁等，所有科研成果均首先落地奥克斯育种基地，快速转化应用。\n\n双方构建的奶牛活体采卵-体外胚胎生产整套产业化繁育技术体系，2016年启动攻关，2019年落地转化，该项目推动单枚胚胎成本由初期数万元降至1000元左右；国产采卵针替代进口，从进口的每支180元降至国产的30元……\n\n“最重要的是，我们实现了种质资源自主可控。”谈到本次“国内首例”的意义，高运东表示，我们改变了依赖进口种质现状，创制出具有国际先进水平的自主耐热奶牛新种质，为种业安全提供核心储备。\n\n（受访者供图）","科技日报","2026-08-27T01:00:00Z",92,{"impact":97,"substance":98,"depth":17,"authority":99,"freshness":100,"relevant":22,"comment":101},28,24,14,8,"国内首例基因编辑耐热奶牛，突破世界难题，兼具产业与科研价值，报道详实。",[103],{"name":93,"url":90},[105,29,106,107],"山东省农科院","畜牧所","耐热荷斯坦牛",{"code":33,"slug":34,"name":35,"path":36,"parent_code":37},[110],{"code":40,"slug":41,"name":42,"path":43,"parent_code":44},{"status":46,"locked":14,"version":47,"method":48,"evidence":112},{"candidates":113,"agricultural_evidence":52},[114,118,122,127],{"code":40,"score":19,"supported":52,"title":115,"abstract":116,"tags":117},[29],[29],[29],{"code":37,"score":63,"supported":52,"title":119,"abstract":120,"tags":121},[65],[65],[],{"code":33,"score":63,"supported":52,"title":123,"abstract":125,"tags":126},[124],"奶牛",[124],[],{"code":69,"score":128,"supported":52,"title":129,"abstract":130,"tags":132},3,[],[131],"种业",[],[134,135],"山东省农科院 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智慧农业","低GI南粳 水稻品种","江苏省农业科学院智慧农业-4395","2026-10-08T00:06:56.447561Z",{"id":369,"title":370,"url":371,"summary":372,"summary_zh":373,"content":8,"source_name":374,"source_url":371,"published_at":375,"category":376,"cover_url":8,"hotness":13,"is_selected":14,"score":377,"score_detail":378,"sources":380,"tags":382,"primary_topic":386,"secondary_topics":387,"classification":388,"search_phrases":409,"slug":412,"view_count":137,"doi":413,"paper":414,"created_at":428},3998,"Enabling the circular bioeconomy: institutional mechanism design for sustainable development of bio-breeding in China","https:\u002F\u002Fdoi.org\u002F10.3389\u002Ffsufs.2026.1699913","The circular bioeconomy provides an opportunity for aligning agricultural innovation with sustainable development goals. Biotechnology breeding (bio-breeding) represents a transformative pathway for improving seed quality, reducing chemical inputs, and building a resource-efficient and circular agricultural system. However, its industrializing transition remains constrained by fragmented regulations, weak intellectual property protection, and limited public acceptance. Existing studies mainly focus on technological development or administrative planning, with limited systematic attention to the institutional mechanisms required to support a sustainable bio-breeding ecosystem. This study employs a qualitative policy analysis approach grounded in the New Haven School of law and policy studies and its “Five Intellectual Tasks.” It develops an analytical framework based on the cyclical and collaborative evolution of “technological innovation—efficiency leap—institutional adaptation—consumer feedback—technological revolution.” The analysis examines China’s bio-breeding value chain and, where relevant, compares regulatory models and industrial pathways in China with those in the United States and the European Union. The analysis identifies four key institutional bottlenecks in the bio-breeding value chain: R&D collaboration, biosafety approval, intellectual property governance, and market acceptance. Lengthy approval processes, misaligned governance structures, insufficient mechanisms for technology transfer and intellectual property protection, and consumer mistrust constrain the effective integration of bio-breeding into a circular economy model. To address these constraints, this study proposes an institutional reform pathway that strengthens technology transfer mechanisms, optimizes the biosafety regulatory system, enhances product regulatory efficiency, and increases consumer participation through labeling systems and public awareness strategies. These findings deepen the theoretical understanding of the institutional transformation required for a circular bioeconomy and provide actionable policy recommendations for supporting sustainable bio-breeding development in China and other emerging economies.","循环生物经济为实现农业创新与可持续发展目标的协同提供了契机。生物技术育种（bio-breeding）是提升种子质量、减少化学投入、构建资源节约型循环农业体系的变革性路径。然而，其产业化转型仍受制于碎片化的监管体系、薄弱的知识产权保护以及有限的公众接受度。现有研究主要聚焦于技术发展或行政规划，对支撑可持续生物育种生态系统所需的制度机制缺乏系统性关注。本研究采用基于纽黑文学派法律与政策研究及其“五项智识任务”的定性政策分析方法，构建了基于“技术创新—效率跃升—制度适配—消费者反馈—技术革命”循环协同演进的分析框架。研究考察了中国生物育种价值链，并在相关处比较了中国与美国、欧盟的监管模式和产业路径。分析识别出生物育种价值链中的四大关键制度瓶颈：研发协作、生物安全审批、知识产权治理和市场接受度。审批流程冗长、治理结构错位、技术转移与知识产权保护机制不足以及消费者信任缺失，制约了生物育种有效融入循环经济模式。针对上述制约，本研究提出了一条制度改革路径，即强化技术转移机制、优化生物安全监管体系、提升产品监管效率，并通过标签制度和公众认知策略增强消费者参与。这些发现深化了对循环生物经济所需制度转型的理论认识，并为支持中国及其他新兴经济体的可持续生物育种发展提供了可操作的政策建议。","Frontiers in Sustainable Food Systems","2026-10-01T00:00:00Z","论文",84,{"impact":150,"substance":150,"depth":17,"authority":99,"freshness":100,"relevant":22,"comment":379},"该研究以新制度主义视角系统剖析中国生物育种价值链的制度瓶颈并提出改革路径，兼具理论深度与政策参考价值，值得进入每日精选。",[381],{"name":374,"url":371},[27,383,28,384,385],"知识产权","生物安全","循环生物经济",{"code":40,"slug":41,"name":42,"path":43,"parent_code":44},[],{"status":46,"locked":14,"version":47,"method":48,"evidence":389},{"candidates":390,"agricultural_evidence":52},[391,395,400,404],{"code":40,"score":261,"supported":52,"title":392,"abstract":393,"tags":394},[],[28],[28],{"code":74,"score":128,"supported":52,"title":396,"abstract":397,"tags":399},[],[398],"technology transfer",[],{"code":69,"score":326,"supported":14,"title":401,"abstract":402,"tags":403},[],[],[383,27],{"code":405,"score":22,"supported":14,"title":406,"abstract":407,"tags":408},"C5",[],[],[384],[410,411],"中国 生物育种 制度机制","生物育种 循环生物经济","中国生物育种制度机制-3998","10.3389\u002Ffsufs.2026.1699913",{"doi":413,"openalex_id":415,"authors":416,"venue":374,"cited_by_count":82,"oa_url":371,"card":421,"direction":425,"ingested_from":427},"W7215104066",[417,419],{"name":418,"orcid":8},"Yu Qin",{"name":420,"orcid":8},"Kezhen Su",{"tldr":422,"method":423,"finding":424,"direction":425,"opportunity":426},"本文分析中国生物育种价值链的制度瓶颈，提出面向循环生物经济的制度改革路径。","采用新港学派“五项智力任务”的定性政策分析，比较中美欧监管模式。","识别研发协作、生物安全审批、知识产权治理和市场接受四大制度瓶颈并给出改革建议。","农业绿色发展与碳","可量化评估制度变革对生物育种创新扩散与循环农业减排的因果效应。","openalex","2026-10-02T23:30:10.035922Z"]