[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"item-826":3,"related-826":57},{"id":4,"title":5,"url":6,"summary":7,"summary_zh":8,"content":9,"source_name":10,"source_url":8,"published_at":11,"category":12,"cover_url":8,"hotness":13,"is_selected":14,"score":15,"score_detail":16,"sources":24,"tags":26,"primary_topic":31,"secondary_topics":37,"classification":38,"search_phrases":51,"slug":54,"view_count":55,"doi":8,"paper":8,"created_at":56},826,"[安徽省农科院]生物育种安徽省实验室韩毅教授团队揭示胞内过氧化氢信号转导新机制——Plant Physiology发表","http:\u002F\u002Fswyz.aaas.org.cn\u002F43505232\u002F70788200.html","生物育种安徽省实验室双聘研究人员、安徽农业大学韩毅教授团队在《Plant Physiology》发表题为HPCA1 and CaM3 contribute to peroxisomal H2O2-driven activation of salicylic acid responses的研究论文。该论文鉴定出过氧化物酶体产生的H₂O₂信号下游的两个核心功能组分——质膜受体激酶HPCA1与钙信号传感蛋白CaM3,为解析胞内活性氧信号的转导层级提供了关键新靶点。研究发现HPCA1功能缺失会完全破坏H₂O₂介导的SA防御响应与GSNOR蛋白稳态。",null,"2026年8月18日，生物育种安徽省实验室双聘研究人员、安徽农业大学韩毅教授团队在《Plant Physiology》杂志发表了题为“HPCA1 and CaM3 contribute to peroxisomal H2O2-driven activation of salicylic acid responses”的研究论文，该论文鉴定出‌过氧化物酶体产生的H₂O₂信号下游的两个核心功能组分——质膜受体激酶HPCA1与钙信号传感蛋白CaM3，为解析胞内活性氧信号的转导层级提供了关键新靶点。\n\nC3植物中约70%的H₂O₂由光呼吸代谢产生，而过氧化物酶体正是这部分H₂O₂的核心生成位点，这类细胞器来源的H₂O₂是驱动植物防御应答的核心信号分子，可触发下游一整套有序的免疫响应程序。韩毅团队前期研究已证实（Plant Cell Environ. 2020; 43(5):1175-1191; Plant Cell Environ. 2026; 49(5):2691-2705），过氧化物酶体H₂O₂可通过激活水杨酸（SA）信号通路调控植物免疫应答，且该免疫过程的功能实现，高度依赖S-亚硝基谷胱甘肽还原酶（GSNOR）的蛋白稳态。然而，直接介导H₂O₂信号精准调控GSNOR蛋白丰度的关键调节因子，至今仍未被明确鉴定，其作用机制尚待系统阐明。\n\n为解析过氧化物酶体H₂O₂调控GSNOR蛋白水平的关键机制，本研究通过酵母双杂交高通量筛选锁定了GSNOR的互作蛋白CaM3。遗传证据显示，在H₂O₂富集的cat2突变体背景下，cam3突变会导致H₂O₂介导的SA积累减少、植物抗病性减弱、细胞程序性死亡减缓，同时GSNOR蛋白水平显著下降。我们进一步将该通路与已知的质膜H₂O₂感知元件HPCA1关联，发现HPCA1功能缺失会完全破坏H₂O₂介导的SA防御响应与GSNOR蛋白稳态; 而过量表达CAM3可有效回补hpca1突变体的SA信号缺陷与GSNOR蛋白水平下调表型，明确CaM3是HPCA1下游H₂O₂信号传导的关键组分。后续实验进一步证实，在H₂O₂富集的环境下，HPCA1和CaM3的功能缺失，均会让GSNOR被细胞自噬通路靶向降解。最终本研究揭示了一条植物免疫调控新路径：HPCA1-CaM3模块通过抑制自噬通路对GSNOR的降解，维持GSNOR的蛋白稳态，从而激活H₂O₂下游的SA有关免疫应答。\n\n安徽农业大学和生物育种安徽省实验室为论文共同第一单位。安徽农业大学生物制造学院、生命科学学院罗龙博士后和博士研究生杨天召为论文共同第一作者，韩毅教授为论文通讯作者。安徽农业大学张宽朝正高级实验师、余梅副教授和江苏省农业科学院戚维聪副研究员参与了相关研究工作。该研究获得了国家自然科学基金、植物抗逆高效全国重点实验室开放基金和安徽省教育科学研究项目（重点项目）的联合资助。","安徽省农业科学院生物育种安徽省实验室 2026年8月20日","2026-08-20T00:00:00Z","报道",10,false,81,{"impact":17,"substance":18,"depth":19,"authority":20,"freshness":21,"relevant":22,"comment":23},20,22,18,13,8,1,"揭示植物免疫新机制，具科研价值，但属基础研究，对农业信息化直接应用有限。",[25],{"name":10,"url":6},[27,28,29,30],"安徽省农科院","Plant Physiology","胞内过氧化氢","HPCA1 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gum)直接抑制病原菌生长,从而增强玉米弯孢叶斑病抗性的全新机制,为基于植物微生物组的抗病育种提供了理论依据和技术路径。研究团队通过EMS诱变群体筛选获得抗弯孢叶斑病突变材料并利用MutMap定位方法鉴定出候选基因。","为解析ZmHPATR1调控微生物组介导抗病性的机制，研究团队结合代谢组和叶际微生物组等分析发现，ZmHPATR1功能缺失能够重塑玉米叶片代谢状态，促进富马酸、叶酸和四氢叶酸等关键有机酸积累，这些有机酸可特异性招募有益细菌鞘氨醇单胞菌定殖富集；从富集叶际分离鉴定的鞘氨醇单胞菌可显著抑制新月弯孢菌，分析发现鞘氨醇单胞菌产生的胞外多糖威兰胶可直接抑制病原菌生长、孢子萌发，破坏病原菌细胞结构，从而增强玉米弯孢叶斑病抗性，构建了“植物基因—代谢物—微生物—病原菌”的四级抗病调控网络（图2）。进一步研究证实ZmHPATR1功能缺失突变体也可增强玉米对小斑病抗性。同时，鞘氨醇单胞菌与威兰胶对玉米小斑病菌（Bipolaris maydis）、玉米大斑病菌（Exserohilum turcicum）、玉米茎基腐病菌（Fusarium verticillioides）等病原真菌均具有显著的拮抗抑制效果，显示其广谱抗病应用潜力。","安徽省农业科学院 生物育种安徽省实验室 2026年8月3日","2026-08-03T00:00:00Z",80,{"impact":18,"substance":70,"depth":17,"authority":71,"freshness":72,"relevant":22,"comment":73},24,12,2,"揭示植物基因-代谢物-微生物-病原菌四级调控网络，为抗病育种提供新路径，但发布已超两周，时效性低。",[75],{"name":66,"url":63},[27,77,78,79,80,81],"生物育种安徽省实验室","李晓玉","ZmHPATR1","鞘氨醇单胞菌","New 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保护视力色：\n\n2026年10月17日，安徽省农作物种业发展论坛暨生物育种前沿技术应用学术交流会在合肥成功召开。本次会议由安徽省作物学会、生物育种安徽省实验室共同主办，安徽昇谷农业科技有限公司承办。会议由安徽省作物学会理事长、安徽省农业科学院副院长李成，学会副理事长、安徽农业大学李金才教授分段主持。来自全省200余名种业领域专家学者、企业家、会员代表和研究生等齐聚一堂，围绕前沿生物育种技术研发与应用开展学术交流与技术研讨。\n\n李成在主持会议时指出，种业是国家战略性、基础性核心产业，是保障国家粮食安全和农产品有效供给的根本支撑。希望通过此次会议，搭建交流合作平台，促进创新链与产业链深度融合，推动生物育种前沿技术从实验室走向田间地头，从科研成果转化为现实生产力，为种业振兴、建设高质高效农业强省贡献智慧与力量。\n\n会议以“生物育种助力江淮粮仓建设”为主题，邀请生物育种安徽省实验室主任吕玉平博士，生物育种安徽省实验室玉米重大创新任务特聘研究员、中国农业大学赖锦盛教授，生物育种安徽省实验室油菜重大创新任务特聘研究员、崖州湾国家实验室油菜创新团队首席科学家、华中农业大学郭亮教授等专家分别围绕“玉米生物育种研究进展”“生物育种新质生产力赋能种业创新”“油菜育种理论、技术和应用”等作大会报告，从基础研究、技术攻关、产业化应用等不同角度分享分享生物育种前沿技术研究进展和生物育种产业化实践经验。","安徽省农业科学院 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聚力生物育种实验室与种质资源中心库建设","https:\u002F\u002Fwww.aaas.org.cn\u002F4303133\u002F71521005.html","10月16日省农科院召开三季度重点工作督查会，院长张正竹表示三季度科技支撑粮油作物大面积单产提升成效明显，育种创新与平台建设推进节奏提速。四季度将倒排工期、挂图作战，聚力攻坚生物育种安徽省实验室、省农业种质资源中心库与凌家湖综合试验基地等重大平台条件建设，建好用好「皖美农科」农技服务综合平台。","10月16日上午，省农科院召开2026年三季度重点工作督查会，全面总结第三季度工作成效，安排部署四季度重点任务。院党组书记、院长张正竹主持会议，院领导李成、戚仁德、张磊出席会议。院属各单位、院直各部门负责同志参加会议。\n\n会议听取了院属各单位、院直各部门年度重点任务落实情况、关键指标完成情况及下一步工作计划。院领导就分管领域工作进行分析点评，提出具体工作要求。\n\n张正竹指出，三季度以来，全院上下深入贯彻省委省政府决策部署，锚定年度目标任务，坚持稳中求进、以进促稳，聚焦主责主业精准发力，各项重点工作阶段性进展扎实见效，科技支撑粮油作物大面积单产提升成效明显，育种创新、技术攻关、平台建设推进节奏不断提速，合作交流、人才培养、党的建设持续加强，以实干实效推动全年工作提质增效。\n\n张正竹强调，四季度是全年冲刺收官的关键时期，要坚决摒弃松劲懈怠思想，紧盯年度重点目标、重点任务、重点项目，倒排工期、挂图作战、闭环推进，逐项梳理盘点、抓紧查漏补缺，确保各项任务圆满完成。要进一步强化工作的主动性、前瞻性和系统性，大力争取平台、项目、资金等各类资源，为明年工作赢得主动。要持续巩固拓展工作成效，一鼓作气、乘势而上，聚力攻坚生物育种安徽省实验室、省农业种质资源中心库、凌家湖综合试验基地等重大平台条件建设，建好用好“皖美农科”农技服务综合平台，加快打造覆盖安徽全域的农业科技服务体系，不断夯实创新发展硬件基础，奋力实现“十五五”良好开局。","安徽省农业科学院 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小】\n\n10月12日，环艺所举办第三季度学术报告会。本次报告会聚焦观赏植物多组学育种、兰花分子育种技术创新、种质资源保育利用及国际学术交流等前沿方向，所内科研人员、研究生等40多人参会。\n\n山东省农科院休闲农业研究所卢昭文博士作“从观赏植物多组学育种到高质量表型驱动的智能预测”报告。以菊花耐旱遗传解析为基础，利用F₁群体开展QTL定位、全基因组关联分析与转录组多组学联合解析；延伸介绍月季耐盐、玫瑰花香分子机制研究，探讨人工智能、植物大模型与基因组学交叉在观赏植物育种中的应用，围绕跨物种基因挖掘、泛基因组解析、育种数据智能利用分享思路，为花卉智能育种提供技术参考。\n\n中国农科院与比利时列日大学联合培养博士生林增裕作“国兰TRV‑VIGS与Ruby可视化瞬时表达体系的建立及应用”报告。针对国兰遗传转化周期长、基因功能验证效率偏低的难题，团队搭建并优化国兰TRV‑VIGS基因沉默体系与Ruby可视化瞬时过表达两套瞬时分析技术，确定最佳侵染参数，完成调控兰花花器官发育、花期、芽再生关键基因的功能验证，突破国兰基因功能研究瓶颈。\n\n环艺所兰花研究室副主任高洁作“观赏园艺研究新篇章：保育、利用与生物技术的融合发展”报告，结合自身访学交流和科研工作经历，详细分析兰科产业发展痛点与科研攻关前沿方向，给参会人员诸多启发和思考；助理研究员苟亚军分享“赴新加坡国立大学开展国际学术交流感想”。结合海外访学经历，总结访学收获；同时介绍自身在兰花花器官发育关键基因挖掘与功能解析上的研究成果，激励青年科研人员拓展国际视野，深化对外学术合作，吸收先进科研理念提升创新能力。\n\n本次报告会搭建高效学术交流平台，展示了观赏园艺领域青年科研人员最新成果，拓宽了科研人员学术视野，促进了跨单位科研思路碰撞，有力推动环艺所兰花及观赏花卉种质创新、分子育种研究，助力高水平科研成果产出。\n\n![Image 1: 图片1.png](http:\u002F\u002Fwww.gdaas.cn\u002Fimg\u002F0\u002F892\u002F892703\u002F1340751.png)\n\n![Image 2: 图片2.png](http:\u002F\u002Fwww.gdaas.cn\u002Fimg\u002F0\u002F892\u002F892704\u002F1340751.png)","广东省农业科学院 2026-10-12","2026-10-12T00:00:00Z",{"impact":13,"substance":94,"depth":71,"authority":71,"freshness":58,"relevant":22,"comment":270},"省级科研院所学术报告会，含多组学育种与国兰基因功能验证等实质技术内容，但属内部学术交流，公共影响有限。",[272],{"name":267,"url":264},[177,274,275,276,277],"分子育种","多组学","观赏园艺","兰花育种",{"code":32,"slug":33,"name":34,"path":35,"parent_code":36},[],{"status":39,"locked":14,"version":40,"method":41,"evidence":281},{"candidates":282,"agricultural_evidence":46},[283,287],{"code":32,"score":20,"supported":46,"title":284,"abstract":285,"tags":286},[274],[274],[274,275],{"code":129,"score":147,"supported":46,"title":288,"abstract":289,"tags":290},[],[177],[177],[292,293],"广东农科院 环艺所 兰花育种","国兰 TRV-VIGS 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