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Journal》。","[English](https:\u002F\u002Fwww.caas.cn\u002Fen)[邮箱](https:\u002F\u002Fmail.caas.cn\u002F)[数字农科院](https:\u002F\u002Fi.caas.cn\u002F)[](https:\u002F\u002Fcaas.cn\u002Fcms\u002Fweb\u002Fsearch\u002Findex.jsp?siteID=cdb01dceb46e48488945d4465e90f221&aba=)\n\n官方微信 \n\n![Image 2](https:\u002F\u002Fcaas.cn\u002Fimages\u002F2023-01\u002F020ac4d3d8b6451782a8702c72604336.jpg)农科专家在线微信公众号\n\n![Image 3](https:\u002F\u002Fcaas.cn\u002Fimages\u002F2023-01\u002Fbf6579e4651e437db31a22cd2249b319.jpg)中国农科院微信公众号\n\n[![Image 4](https:\u002F\u002Fcaas.cn\u002Fstatic2022\u002Fimages\u002Fmenu_logo.png)](https:\u002F\u002Fcaas.cn\u002Findex.htm)\n\n*   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Journal）》上。\n\n杂草防控是紫花苜蓿生产中的关键环节，直接影响饲草产量品质与生产效益。然而，长期单一施用除草剂会引发杂草抗药性上升、土壤残留等问题，制约紫花苜蓿绿色可持续规模化种植。\n\n研究团队构建了适配紫花苜蓿的高效引导编辑系统，并进一步对三个抗除草剂靶标基因同时定点突变，创制出了兼具烟嘧磺隆高抗性与高效氟吡甲禾灵耐受性的紫花苜蓿新种质。该研究首次在紫花苜蓿中实现了多基因引导编辑，为紫花苜蓿生物育种与多抗种质创新提供了新型技术工具和优异种质资源。\n\n该研究得到国家自然科学基金、中国农业科学院科技创新工程等项目支持。（通讯员：崔艳）\n\n原文链接：https:\u002F\u002Fonlinelibrary.wiley.com\u002Fdoi\u002F10.1111\u002Fpbi.70752\n\n![Image 8: image.png](https:\u002F\u002Fcaas.cn\u002Fimages\u002F2026-09\u002Fff58b03ac069469f9b2a4c67041dac21.png)\n\n打印本页\n\n关闭本页\n\n[院网信息发布与管理](https:\u002F\u002Fcaas.cn\u002Fywxxfbygl\u002Findex.htm)[最新动态](https:\u002F\u002Fcaas.cn\u002Fywxxfbygl\u002Findex.htm)\n\n*   [科技赋能沃野 夯实中原粮仓 专家下沉一线护航玉米丰产丰收](https:\u002F\u002Fcaas.cn\u002Fxwzx\u002Fhzdznew\u002F21942b3ab22c47fc935218df967152b7.htm)2026-09-28  \n*   [秋收图景](https:\u002F\u002Fwww.caas.cn\u002Fzt\u002F2026qstj\u002Findex.htm)2026-09-28  \n*   [ARC生物耦合技术赋能兰考花生产业增产增效](https:\u002F\u002Fcaas.cn\u002Fxwzx\u002Fkyhd\u002Ffc42a7cb57414940a787e12f23de332e.htm)2026-09-28  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京公网安备11010802048565号](http:\u002F\u002Fwww.beian.gov.cn\u002Fportal\u002FregisterSystemInfo?recordcode=11010802048565)","中国农业科学院网·2026年10月","2026-10-02T00:00:00Z",{"impact":642,"substance":321,"depth":643,"authority":585,"freshness":173,"relevant":455,"comment":644},24,16,"国家级科研机构首次在苜蓿中实现多基因引导编辑，属生物育种领域实质性突破，具备进入每日精选的价值。",[646,647,649],{"name":639,"url":636},{"name":648,"url":576},"中国科学报·2026年10月4日",{"name":650,"url":651},"中国科学报 2026-10-04","https:\u002F\u002Fnews.sciencenet.cn\u002Fhtmlnews\u002F2026\u002F10\u002F572493.shtm",[590,653,591,592,654],"生物育种","除草剂抗性",{"code":364,"slug":365,"name":366,"path":367,"parent_code":332},[657,658],{"code":256,"slug":257,"name":258,"path":259,"parent_code":200},{"code":104,"slug":105,"name":106,"path":107,"parent_code":72},{"status":600,"locked":582,"version":4,"method":601,"evidence":660},{"candidates":661,"agricultural_evidence":605},[662,666,670,674,678],{"code":364,"score":585,"supported":605,"title":663,"abstract":664,"tags":665},[607],[609,607],[592],{"code":256,"score":416,"supported":605,"title":667,"abstract":668,"tags":669},[607],[607],[592],{"code":104,"score":524,"supported":605,"title":671,"abstract":672,"tags":673},[617],[617],[],{"code":88,"score":69,"supported":582,"title":675,"abstract":676,"tags":677},[],[],[591,653],{"code":80,"score":455,"supported":582,"title":679,"abstract":680,"tags":681},[],[],[590],[683,684],"中国农科院生物所 紫花苜蓿","苜蓿 引导编辑 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生物所开发引导编辑系统并创制耐双除草剂紫花苜蓿新种质\n\n近日，中国农业科学院生物技术研究所饲草作物功能基因组创新团队开发了紫花苜蓿高效引导编辑技术体系，并创制了耐双除草剂紫花苜蓿新种质，为饲草绿色轻简化栽培和分子育种提供了重要技术工具与种质资源。相关研究成果发表在《植物生物技术杂志（Plant Biotechnology Journal）》上。\n\n![Image 1](https:\u002F\u002Fbri.caas.cn\u002Fimages\u002F2026-09\u002F3b6cc618b82e41f0935363d23fe6c309.png)\n\n杂草防控是紫花苜蓿生产中的关键环节。长期单一施用除草剂易诱导杂草产生抗药性，同时带来土壤残留风险。创制新型多抗除草剂紫花苜蓿种质，对提升饲草产量与品质、降低田间管理成本、推进产业绿色可持续发展具有重要意义与应用前景。\n\n研究团队通过优化驱动引导编辑核心元件的启动子，构建了适用于紫花苜蓿的引导编辑系统。进一步对MsALS1、MsALS2及MsACC1基因同时定点突变，创制出了兼具烟嘧磺隆高抗性与高效氟吡甲禾灵耐受性的紫花苜蓿新种质。该研究首次在紫花苜蓿中实现了多基因引导编辑，为紫花苜蓿生物育种与多抗种质创新提供了新型技术工具和优异种质资源。\n\n生物所博士研究生李世豪为论文第一作者。牛丽芳研究员、林浩研究员为共同通讯作者。中国农业大学宗媛教授分享了pB-CMPE-ePPEplus载体、广州大学关跃峰教授分享了pGES401载体。该研究工作得到了国家自然科学基金(32325035)和中国农业科学院科技创新工程等项目的支持。\n\n原文链接：https:\u002F\u002Fonlinelibrary.wiley.com\u002Fdoi\u002F10.1111\u002Fpbi.70752","中国农科院生物所 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