Researchers establish G0 founder population carrying targeted mutations in marine mollusks
Although genome-editing-based breeding has advanced rapidly in aquaculture, progress in marine mollusks has lagged behind. The main challenge is not genome editing itself, but rather rearing the few edited larvae through metamorphosis to establish a viable G0 founder population.
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该研究通过单孔隔离培育与优化变态诱导，将基因编辑鲍鱼幼虫存活率提升至90%以上，并建立个体基因分型流程，为软体动物基因编辑育种提供可复用的技术路径。
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